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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HISPPD2A
All Species:
14.55
Human Site:
T1217
Identified Species:
26.67
UniProt:
Q6PFW1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PFW1
NP_001019634.1
1433
159521
T1217
G
L
G
L
L
Q
E
T
P
G
S
G
A
Q
E
Chimpanzee
Pan troglodytes
XP_510352
1408
156588
T1192
G
L
G
L
L
Q
E
T
P
G
S
G
A
Q
E
Rhesus Macaque
Macaca mulatta
XP_001098229
1243
140375
Y1040
V
V
S
E
N
A
N
Y
L
R
T
P
R
T
L
Dog
Lupus familis
XP_535450
1457
162086
E1214
E
P
S
Q
S
S
Q
E
P
P
V
E
T
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
A2ARP1
1436
159904
T1212
G
F
G
L
L
Q
E
T
P
G
D
G
T
R
E
Rat
Rattus norvegicus
P0C644
1434
159600
T1214
G
L
G
L
L
Q
E
T
P
G
D
G
T
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505793
1285
145199
P1082
I
T
S
S
P
V
S
P
K
S
L
A
F
T
S
Chicken
Gallus gallus
XP_413955
1359
152194
S1153
T
V
S
S
A
G
P
S
S
P
T
S
L
D
S
Frog
Xenopus laevis
Q5XHF8
1131
128702
P928
P
S
G
F
G
Y
R
P
A
S
Q
E
N
E
S
Zebra Danio
Brachydanio rerio
XP_684718
1352
151299
S1147
Y
I
P
H
R
V
L
S
S
S
V
S
L
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR59
1696
188659
K1300
L
W
P
Q
D
I
V
K
A
A
E
D
E
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91309
1323
150102
R1120
D
L
L
D
Q
T
K
R
A
M
A
M
N
S
I
Sea Urchin
Strong. purpuratus
XP_001194114
1337
149934
K1130
T
Y
T
P
Q
R
V
K
P
S
S
L
N
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
57.5
90.1
N.A.
90.1
89.2
N.A.
58.9
70.2
57.8
68.8
N.A.
44.1
N.A.
39.7
47.7
Protein Similarity:
100
97.9
67.8
92.5
N.A.
93.3
92.4
N.A.
69.7
79.6
66.9
78.1
N.A.
57.7
N.A.
56.3
62.5
P-Site Identity:
100
100
0
6.6
N.A.
73.3
80
N.A.
0
0
6.6
0
N.A.
0
N.A.
6.6
13.3
P-Site Similarity:
100
100
13.3
20
N.A.
80
80
N.A.
0
20
13.3
26.6
N.A.
6.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
0
24
8
8
8
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
8
0
0
0
0
0
16
8
0
8
0
% D
% Glu:
8
0
0
8
0
0
31
8
0
0
8
16
8
16
31
% E
% Phe:
0
8
0
8
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
31
0
39
0
8
8
0
0
0
31
0
31
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
8
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
8
16
8
0
0
0
0
0
0
% K
% Leu:
8
31
8
31
31
0
8
0
8
0
8
8
16
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
0
0
0
0
0
24
0
0
% N
% Pro:
8
8
16
8
8
0
8
16
47
16
0
8
0
8
0
% P
% Gln:
0
0
0
16
16
31
8
0
0
0
8
0
0
16
16
% Q
% Arg:
0
0
0
0
8
8
8
8
0
8
0
0
8
16
8
% R
% Ser:
0
8
31
16
8
8
8
16
16
31
24
16
0
16
24
% S
% Thr:
16
8
8
0
0
8
0
31
0
0
16
0
24
24
0
% T
% Val:
8
16
0
0
0
16
16
0
0
0
16
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
8
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _