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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HISPPD2A All Species: 6.06
Human Site: T861 Identified Species: 11.11
UniProt: Q6PFW1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PFW1 NP_001019634.1 1433 159521 T861 Y G G L L D E T Q D A Q W Q R
Chimpanzee Pan troglodytes XP_510352 1408 156588 E838 T R L Y F T S E S H V H S L L
Rhesus Macaque Macaca mulatta XP_001098229 1243 140375 S686 H R M E D P K S S D I Q L Y H
Dog Lupus familis XP_535450 1457 162086 T857 Y G G L L D E T Q D A Q W Q R
Cat Felis silvestris
Mouse Mus musculus A2ARP1 1436 159904 E856 R Y G G L L D E T Q D A Q W Q
Rat Rattus norvegicus P0C644 1434 159600 E858 R Y G G L L D E T K D A Q W Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505793 1285 145199 K728 N P V K T C D K V Y S L I Q S
Chicken Gallus gallus XP_413955 1359 152194 Q799 L P L I K K I Q L D L Q R T H
Frog Xenopus laevis Q5XHF8 1131 128702 L574 H S T Y R H D L K I Y A S D E
Zebra Danio Brachydanio rerio XP_684718 1352 151299 C791 L D I A Y A Y C L P L V K K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VR59 1696 188659 V877 Y G G L L N V V T D E Q W R R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91309 1323 150102 V766 F E R M Y V C V K N M A D I V
Sea Urchin Strong. purpuratus XP_001194114 1337 149934 D776 L L K K I R S D L H R I N S N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 57.5 90.1 N.A. 90.1 89.2 N.A. 58.9 70.2 57.8 68.8 N.A. 44.1 N.A. 39.7 47.7
Protein Similarity: 100 97.9 67.8 92.5 N.A. 93.3 92.4 N.A. 69.7 79.6 66.9 78.1 N.A. 57.7 N.A. 56.3 62.5
P-Site Identity: 100 0 13.3 100 N.A. 13.3 13.3 N.A. 6.6 13.3 0 0 N.A. 60 N.A. 0 0
P-Site Similarity: 100 0 33.3 100 N.A. 26.6 26.6 N.A. 20 20 20 6.6 N.A. 73.3 N.A. 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 0 0 0 0 16 31 0 0 0 % A
% Cys: 0 0 0 0 0 8 8 8 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 8 16 31 8 0 39 16 0 8 8 0 % D
% Glu: 0 8 0 8 0 0 16 24 0 0 8 0 0 0 8 % E
% Phe: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 24 39 16 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 16 0 0 0 0 8 0 0 0 16 0 8 0 0 16 % H
% Ile: 0 0 8 8 8 0 8 0 0 8 8 8 8 8 8 % I
% Lys: 0 0 8 16 8 8 8 8 16 8 0 0 8 8 0 % K
% Leu: 24 8 16 24 39 16 0 8 24 0 16 8 8 8 8 % L
% Met: 0 0 8 8 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 8 0 0 0 0 8 0 0 0 8 0 0 8 0 8 % N
% Pro: 0 16 0 0 0 8 0 0 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 16 8 0 39 16 24 16 % Q
% Arg: 16 16 8 0 8 8 0 0 0 0 8 0 8 8 24 % R
% Ser: 0 8 0 0 0 0 16 8 16 0 8 0 16 8 8 % S
% Thr: 8 0 8 0 8 8 0 16 24 0 0 0 0 8 0 % T
% Val: 0 0 8 0 0 8 8 16 8 0 8 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 24 16 0 % W
% Tyr: 24 16 0 16 16 0 8 0 0 8 8 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _