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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HISPPD2A
All Species:
17.88
Human Site:
T963
Identified Species:
32.78
UniProt:
Q6PFW1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PFW1
NP_001019634.1
1433
159521
T963
E
P
D
R
A
L
Q
T
S
P
Q
P
P
E
G
Chimpanzee
Pan troglodytes
XP_510352
1408
156588
S940
E
M
K
T
N
Q
G
S
M
E
N
L
C
P
G
Rhesus Macaque
Macaca mulatta
XP_001098229
1243
140375
S788
P
L
V
R
K
I
R
S
D
L
Q
R
T
Q
D
Dog
Lupus familis
XP_535450
1457
162086
T959
E
P
D
R
A
L
Q
T
S
P
Q
P
L
E
G
Cat
Felis silvestris
Mouse
Mus musculus
A2ARP1
1436
159904
T958
E
P
D
R
A
L
Q
T
S
P
Q
P
V
E
G
Rat
Rattus norvegicus
P0C644
1434
159600
T960
E
P
D
R
A
L
Q
T
S
P
Q
P
V
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505793
1285
145199
S830
I
P
Q
E
Y
G
I
S
K
V
E
K
L
E
I
Chicken
Gallus gallus
XP_413955
1359
152194
V901
S
S
E
E
R
F
H
V
E
L
H
F
S
P
G
Frog
Xenopus laevis
Q5XHF8
1131
128702
T676
F
I
K
N
P
V
K
T
C
D
K
V
Y
S
L
Zebra Danio
Brachydanio rerio
XP_684718
1352
151299
I893
N
Y
M
T
Q
I
V
I
M
L
Y
E
D
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR59
1696
188659
E979
N
D
S
N
S
G
E
E
R
E
G
K
K
R
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91309
1323
150102
Q868
S
V
D
D
K
K
W
Q
R
A
M
N
F
L
S
Sea Urchin
Strong. purpuratus
XP_001194114
1337
149934
L878
D
D
R
F
R
V
E
L
H
F
S
P
G
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
57.5
90.1
N.A.
90.1
89.2
N.A.
58.9
70.2
57.8
68.8
N.A.
44.1
N.A.
39.7
47.7
Protein Similarity:
100
97.9
67.8
92.5
N.A.
93.3
92.4
N.A.
69.7
79.6
66.9
78.1
N.A.
57.7
N.A.
56.3
62.5
P-Site Identity:
100
13.3
13.3
93.3
N.A.
93.3
93.3
N.A.
13.3
6.6
6.6
0
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
20
40
93.3
N.A.
93.3
93.3
N.A.
26.6
13.3
26.6
6.6
N.A.
20
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
31
0
0
0
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% C
% Asp:
8
16
39
8
0
0
0
0
8
8
0
0
8
0
8
% D
% Glu:
39
0
8
16
0
0
16
8
8
16
8
8
0
39
0
% E
% Phe:
8
0
0
8
0
8
0
0
0
8
0
8
8
0
0
% F
% Gly:
0
0
0
0
0
16
8
0
0
0
8
0
8
0
54
% G
% His:
0
0
0
0
0
0
8
0
8
0
8
0
0
0
0
% H
% Ile:
8
8
0
0
0
16
8
8
0
0
0
0
0
0
8
% I
% Lys:
0
0
16
0
16
8
8
0
8
0
8
16
8
0
8
% K
% Leu:
0
8
0
0
0
31
0
8
0
24
0
8
16
8
8
% L
% Met:
0
8
8
0
0
0
0
0
16
0
8
0
0
0
0
% M
% Asn:
16
0
0
16
8
0
0
0
0
0
8
8
0
8
8
% N
% Pro:
8
39
0
0
8
0
0
0
0
31
0
39
8
16
0
% P
% Gln:
0
0
8
0
8
8
31
8
0
0
39
0
0
8
0
% Q
% Arg:
0
0
8
39
16
0
8
0
16
0
0
8
0
8
0
% R
% Ser:
16
8
8
0
8
0
0
24
31
0
8
0
8
8
8
% S
% Thr:
0
0
0
16
0
0
0
39
0
0
0
0
8
0
0
% T
% Val:
0
8
8
0
0
16
8
8
0
8
0
8
16
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
0
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _