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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HISPPD2A
All Species:
15.76
Human Site:
T994
Identified Species:
28.89
UniProt:
Q6PFW1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PFW1
NP_001019634.1
1433
159521
T994
S
M
E
V
L
S
E
T
S
S
S
R
P
G
G
Chimpanzee
Pan troglodytes
XP_510352
1408
156588
R971
A
E
G
P
G
L
P
R
R
S
P
L
I
R
N
Rhesus Macaque
Macaca mulatta
XP_001098229
1243
140375
T819
S
P
E
R
H
V
R
T
R
L
Y
F
T
S
E
Dog
Lupus familis
XP_535450
1457
162086
T990
S
M
E
V
L
S
E
T
S
S
S
R
P
G
S
Cat
Felis silvestris
Mouse
Mus musculus
A2ARP1
1436
159904
T989
S
M
E
V
L
S
E
T
S
S
S
R
P
G
G
Rat
Rattus norvegicus
P0C644
1434
159600
T991
S
M
E
V
L
S
E
T
S
S
S
R
P
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505793
1285
145199
T861
Q
R
T
Q
D
D
D
T
V
N
K
L
H
P
L
Chicken
Gallus gallus
XP_413955
1359
152194
E932
R
P
A
S
A
E
S
E
D
K
K
A
D
Q
G
Frog
Xenopus laevis
Q5XHF8
1131
128702
H707
F
A
D
I
Q
L
Y
H
S
E
T
L
E
L
M
Zebra Danio
Brachydanio rerio
XP_684718
1352
151299
E924
P
G
V
K
V
S
E
E
E
S
A
P
M
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR59
1696
188659
E1010
A
F
G
F
N
R
L
E
L
R
S
K
Q
F
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91309
1323
150102
D899
E
D
S
R
K
E
N
D
E
A
D
T
G
P
R
Sea Urchin
Strong. purpuratus
XP_001194114
1337
149934
S909
V
H
N
S
G
N
A
S
P
Y
E
N
N
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
57.5
90.1
N.A.
90.1
89.2
N.A.
58.9
70.2
57.8
68.8
N.A.
44.1
N.A.
39.7
47.7
Protein Similarity:
100
97.9
67.8
92.5
N.A.
93.3
92.4
N.A.
69.7
79.6
66.9
78.1
N.A.
57.7
N.A.
56.3
62.5
P-Site Identity:
100
6.6
20
93.3
N.A.
100
100
N.A.
6.6
6.6
6.6
26.6
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
13.3
20
93.3
N.A.
100
100
N.A.
20
6.6
26.6
40
N.A.
20
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
0
8
0
8
0
0
8
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
8
8
8
8
8
0
8
0
8
0
0
% D
% Glu:
8
8
39
0
0
16
39
24
16
8
8
0
8
0
16
% E
% Phe:
8
8
0
8
0
0
0
0
0
0
0
8
0
8
8
% F
% Gly:
0
8
16
0
16
0
0
0
0
0
0
0
8
39
31
% G
% His:
0
8
0
0
8
0
0
8
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
8
0
0
0
0
8
16
8
0
0
8
% K
% Leu:
0
0
0
0
31
16
8
0
8
8
0
24
0
8
8
% L
% Met:
0
31
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
8
0
8
8
8
0
0
8
0
8
8
0
8
% N
% Pro:
8
16
0
8
0
0
8
0
8
0
8
8
31
16
0
% P
% Gln:
8
0
0
8
8
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
8
8
0
16
0
8
8
8
16
8
0
31
0
8
8
% R
% Ser:
39
0
8
16
0
39
8
8
39
47
39
0
0
16
8
% S
% Thr:
0
0
8
0
0
0
0
47
0
0
8
8
8
0
0
% T
% Val:
8
0
8
31
8
8
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _