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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HISPPD2A
All Species:
23.33
Human Site:
Y247
Identified Species:
42.78
UniProt:
Q6PFW1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PFW1
NP_001019634.1
1433
159521
Y247
R
K
T
G
S
Y
I
Y
E
E
F
M
P
T
D
Chimpanzee
Pan troglodytes
XP_510352
1408
156588
Y247
R
K
T
G
S
Y
I
Y
E
E
F
M
P
T
D
Rhesus Macaque
Macaca mulatta
XP_001098229
1243
140375
V121
A
K
L
R
N
P
F
V
I
N
D
L
N
M
Q
Dog
Lupus familis
XP_535450
1457
162086
Y247
R
K
T
G
S
Y
I
Y
E
E
F
M
P
T
D
Cat
Felis silvestris
Mouse
Mus musculus
A2ARP1
1436
159904
Y247
R
K
T
G
S
Y
I
Y
E
E
F
M
P
T
D
Rat
Rattus norvegicus
P0C644
1434
159600
Y249
R
K
T
G
S
Y
I
Y
E
E
F
M
P
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505793
1285
145199
F163
L
C
D
C
L
V
S
F
H
S
K
G
F
P
L
Chicken
Gallus gallus
XP_413955
1359
152194
F223
G
G
G
S
Q
R
L
F
R
K
I
G
S
R
S
Frog
Xenopus laevis
Q5XHF8
1131
128702
D9
S
V
S
A
T
E
N
D
V
P
R
F
F
V
G
Zebra Danio
Brachydanio rerio
XP_684718
1352
151299
F224
G
G
G
S
Q
R
L
F
R
K
I
G
S
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR59
1696
188659
Y259
R
K
T
G
S
F
I
Y
E
D
F
M
P
T
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91309
1323
150102
S201
S
S
W
Y
S
P
K
S
E
V
R
K
E
G
S
Sea Urchin
Strong. purpuratus
XP_001194114
1337
149934
P210
N
R
S
S
I
Y
S
P
E
S
R
I
R
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
57.5
90.1
N.A.
90.1
89.2
N.A.
58.9
70.2
57.8
68.8
N.A.
44.1
N.A.
39.7
47.7
Protein Similarity:
100
97.9
67.8
92.5
N.A.
93.3
92.4
N.A.
69.7
79.6
66.9
78.1
N.A.
57.7
N.A.
56.3
62.5
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
0
0
0
0
N.A.
86.6
N.A.
13.3
13.3
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
6.6
20
13.3
20
N.A.
100
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
8
0
8
8
0
0
0
47
% D
% Glu:
0
0
0
0
0
8
0
0
62
39
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
8
8
24
0
0
47
8
16
0
0
% F
% Gly:
16
16
16
47
0
0
0
0
0
0
0
24
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
47
0
8
0
16
8
0
0
0
% I
% Lys:
0
54
0
0
0
0
8
0
0
16
8
8
0
0
0
% K
% Leu:
8
0
8
0
8
0
16
0
0
0
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
47
0
8
0
% M
% Asn:
8
0
0
0
8
0
8
0
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
16
0
8
0
8
0
0
47
8
0
% P
% Gln:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
47
8
0
8
0
16
0
0
16
0
24
0
8
24
0
% R
% Ser:
16
8
16
24
54
0
16
8
0
16
0
0
16
0
24
% S
% Thr:
0
0
47
0
8
0
0
0
0
0
0
0
0
47
0
% T
% Val:
0
8
0
0
0
8
0
8
8
8
0
0
0
8
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
47
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _