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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HISPPD2A
All Species:
4.55
Human Site:
Y822
Identified Species:
8.33
UniProt:
Q6PFW1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PFW1
NP_001019634.1
1433
159521
Y822
H
P
L
C
Y
L
R
Y
S
R
G
V
L
S
P
Chimpanzee
Pan troglodytes
XP_510352
1408
156588
L799
L
P
L
L
R
K
I
L
L
D
L
Q
R
T
H
Rhesus Macaque
Macaca mulatta
XP_001098229
1243
140375
I647
K
L
T
P
S
G
S
I
S
L
I
K
S
M
H
Dog
Lupus familis
XP_535450
1457
162086
Y818
V
N
K
L
H
P
L
Y
S
R
G
V
L
S
P
Cat
Felis silvestris
Mouse
Mus musculus
A2ARP1
1436
159904
L817
S
V
N
K
L
H
P
L
Y
S
R
G
V
L
S
Rat
Rattus norvegicus
P0C644
1434
159600
L819
S
V
N
K
L
H
P
L
Y
S
R
G
V
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505793
1285
145199
I689
V
K
A
R
L
H
E
I
L
Q
R
D
R
E
F
Chicken
Gallus gallus
XP_413955
1359
152194
L760
K
L
E
G
T
A
E
L
F
R
F
S
K
A
L
Frog
Xenopus laevis
Q5XHF8
1131
128702
V535
E
L
T
P
A
G
R
V
Q
A
E
E
L
G
R
Zebra Danio
Brachydanio rerio
XP_684718
1352
151299
L752
D
V
Q
H
N
S
S
L
G
L
E
D
T
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR59
1696
188659
Y838
M
N
R
L
N
P
H
Y
S
H
G
V
A
S
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91309
1323
150102
V727
R
K
N
K
H
G
E
V
E
F
D
I
S
K
I
Sea Urchin
Strong. purpuratus
XP_001194114
1337
149934
N737
S
H
M
D
E
L
Y
N
S
A
E
M
L
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
57.5
90.1
N.A.
90.1
89.2
N.A.
58.9
70.2
57.8
68.8
N.A.
44.1
N.A.
39.7
47.7
Protein Similarity:
100
97.9
67.8
92.5
N.A.
93.3
92.4
N.A.
69.7
79.6
66.9
78.1
N.A.
57.7
N.A.
56.3
62.5
P-Site Identity:
100
13.3
6.6
53.3
N.A.
0
0
N.A.
0
6.6
13.3
0
N.A.
40
N.A.
0
20
P-Site Similarity:
100
20
6.6
60
N.A.
6.6
6.6
N.A.
6.6
13.3
13.3
0
N.A.
40
N.A.
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
0
0
0
16
0
0
8
16
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
0
8
8
16
0
0
8
% D
% Glu:
8
0
8
0
8
0
24
0
8
0
24
8
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
8
8
0
0
0
8
% F
% Gly:
0
0
0
8
0
24
0
0
8
0
24
16
0
8
0
% G
% His:
8
8
0
8
16
24
8
0
0
8
0
0
0
0
16
% H
% Ile:
0
0
0
0
0
0
8
16
0
0
8
8
0
0
8
% I
% Lys:
16
16
8
24
0
8
0
0
0
0
0
8
8
8
0
% K
% Leu:
8
24
16
24
24
16
8
39
16
16
8
0
31
24
8
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
16
24
0
16
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
16
0
16
0
16
16
0
0
0
0
0
0
0
24
% P
% Gln:
0
0
8
0
0
0
0
0
8
8
0
8
0
0
0
% Q
% Arg:
8
0
8
8
8
0
16
0
0
24
24
0
16
0
8
% R
% Ser:
24
0
0
0
8
8
16
0
39
16
0
8
16
24
16
% S
% Thr:
0
0
16
0
8
0
0
0
0
0
0
0
8
8
0
% T
% Val:
16
24
0
0
0
0
0
16
0
0
0
24
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
24
16
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _