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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC37
All Species:
13.94
Human Site:
T254
Identified Species:
38.33
UniProt:
Q6PGP7
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PGP7
NP_055454.1
1564
175486
T254
L
I
E
S
G
N
L
T
D
E
G
Q
Q
Y
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536294
1562
175017
T254
L
I
E
S
G
S
L
T
D
E
G
Q
Q
Y
C
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516104
640
72255
Chicken
Gallus gallus
XP_424706
1562
174693
S254
F
I
Q
S
G
T
L
S
E
E
A
L
Q
Y
F
Frog
Xenopus laevis
Q6DFB8
1564
175367
T254
Y
I
K
S
G
D
I
T
E
E
A
I
C
C
Y
Zebra Danio
Brachydanio rerio
XP_002662144
1566
173769
S255
Y
I
Q
T
G
D
C
S
E
E
A
V
S
C
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610452
1233
139600
R15
K
A
L
I
K
D
I
R
E
T
I
K
L
G
K
Honey Bee
Apis mellifera
XP_395911
1096
125804
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001191373
1475
163379
T242
I
Y
P
L
E
K
L
T
E
I
I
M
I
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92
N.A.
N.A.
N.A.
N.A.
32
67
61.7
55.8
N.A.
23.6
25.4
N.A.
34
Protein Similarity:
100
N.A.
N.A.
96
N.A.
N.A.
N.A.
N.A.
35.9
81.3
78.2
72.2
N.A.
41.3
40.2
N.A.
53.5
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
0
46.6
33.3
20
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
0
66.6
60
53.3
N.A.
26.6
0
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
0
0
0
0
34
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
12
23
23
% C
% Asp:
0
0
0
0
0
34
0
0
23
0
0
0
0
0
0
% D
% Glu:
0
0
23
0
12
0
0
0
56
56
0
0
0
12
0
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% F
% Gly:
0
0
0
0
56
0
0
0
0
0
23
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
56
0
12
0
0
23
0
0
12
23
12
12
0
0
% I
% Lys:
12
0
12
0
12
12
0
0
0
0
0
12
0
0
12
% K
% Leu:
23
0
12
12
0
0
45
0
0
0
0
12
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
23
0
0
0
0
0
0
0
0
23
34
0
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
45
0
12
0
23
0
0
0
0
12
0
0
% S
% Thr:
0
0
0
12
0
12
0
45
0
12
0
0
0
0
12
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
23
12
0
0
0
0
0
0
0
0
0
0
0
34
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _