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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCUN1D2 All Species: 19.55
Human Site: S257 Identified Species: 30.71
UniProt: Q6PH85 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PH85 NP_001014305.1 259 30179 S257 V V T G G K R S L F _ _ _ _ _
Chimpanzee Pan troglodytes XP_509747 276 31975 S274 V V T G G K R S L F _ _ _ _ _
Rhesus Macaque Macaca mulatta XP_001105171 427 47916 S425 V V T G G K R S L F _ _ _ _ _
Dog Lupus familis XP_848655 244 28287 T242 Q I A G T K S T T V _ _ _ _ _
Cat Felis silvestris
Mouse Mus musculus Q8BZJ7 259 30050 S257 V V T G G R R S P F _ _ _ _ _
Rat Rattus norvegicus Q4V8B2 304 34332 L291 E V E G R G A L S S G P E G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515130 282 32978 R280 L V T G G K R R T F _ _ _ _ _
Chicken Gallus gallus Q5ZKU1 259 30091 T257 Q I A G T K S T T V _ _ _ _ _
Frog Xenopus laevis Q6DFA1 303 34608 T286 R R K S E E K T D C I P C L G
Zebra Danio Brachydanio rerio Q5RHX6 280 32402
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUQ8 288 33676 S253 N D H L K E D S S P A S G Y Q
Honey Bee Apis mellifera XP_623120 254 29936
Nematode Worm Caenorhab. elegans Q9U3C8 295 34115 G281 N L N Y P K P G N A S N D Q Q
Sea Urchin Strong. purpuratus XP_795498 274 32217
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12395 269 32185 L265 I D E F Y E C L Q D Q Q _ _ _
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.7 59.4 72.5 N.A. 91.1 35.2 N.A. 75.8 77.2 32 29.6 N.A. 54.1 65.2 36.2 66
Protein Similarity: 100 93.8 60.1 85.7 N.A. 97.3 49.6 N.A. 84.7 90.3 49.5 49.6 N.A. 69 80.3 54.9 79.9
P-Site Identity: 100 100 100 20 N.A. 80 13.3 N.A. 70 20 0 0 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 100 100 40 N.A. 90 26.6 N.A. 80 40 33.3 0 N.A. 26.6 0 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 16.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 0 0 0 7 0 0 7 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 7 0 0 7 0 0 % C
% Asp: 0 14 0 0 0 0 7 0 7 7 0 0 7 0 0 % D
% Glu: 7 0 14 0 7 20 0 0 0 0 0 0 7 0 0 % E
% Phe: 0 0 0 7 0 0 0 0 0 34 0 0 0 0 0 % F
% Gly: 0 0 0 54 34 7 0 7 0 0 7 0 7 7 7 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 14 0 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 7 0 7 47 7 0 0 0 0 0 0 0 0 % K
% Leu: 7 7 0 7 0 0 0 14 20 0 0 0 0 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 14 0 7 0 0 0 0 0 7 0 0 7 0 0 0 % N
% Pro: 0 0 0 0 7 0 7 0 7 7 0 14 0 0 0 % P
% Gln: 14 0 0 0 0 0 0 0 7 0 7 7 0 7 14 % Q
% Arg: 7 7 0 0 7 7 34 7 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 7 0 0 14 34 14 7 7 7 0 0 0 % S
% Thr: 0 0 34 0 14 0 0 20 20 0 0 0 0 0 0 % T
% Val: 27 40 0 0 0 0 0 0 0 14 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 7 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 47 47 54 54 54 % _