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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ULK3
All Species:
40.61
Human Site:
S227
Identified Species:
59.56
UniProt:
Q6PHR2
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PHR2
NP_001092906.1
472
53444
S227
E
L
E
E
K
I
R
S
N
R
V
I
E
L
P
Chimpanzee
Pan troglodytes
XP_510672
472
53351
S227
E
L
E
E
K
I
R
S
N
R
V
I
E
L
P
Rhesus Macaque
Macaca mulatta
XP_001098063
525
59288
S227
E
L
E
E
K
I
R
S
N
R
V
I
E
L
P
Dog
Lupus familis
XP_544776
581
65042
S336
E
L
E
E
K
I
R
S
N
R
V
I
K
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3U3Q1
472
53553
S227
E
L
E
E
K
I
R
S
N
R
V
I
E
L
P
Rat
Rattus norvegicus
XP_001077085
474
53543
S227
E
L
E
E
K
I
R
S
N
R
V
I
E
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJH6
468
53047
S227
E
L
E
E
K
I
R
S
D
R
A
I
E
L
P
Frog
Xenopus laevis
Q4V7Q6
468
53109
S226
E
L
E
E
K
I
L
S
H
K
T
I
E
L
P
Zebra Danio
Brachydanio rerio
NP_001082941
468
53407
S224
E
L
E
E
K
I
R
S
E
R
P
V
E
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731331
520
59745
K222
E
L
L
L
R
I
R
K
A
E
A
I
T
L
P
Honey Bee
Apis mellifera
XP_396911
480
55199
D221
E
L
I
E
K
I
K
D
C
R
S
I
E
L
P
Nematode Worm
Caenorhab. elegans
Q23023
856
94874
K232
Q
L
K
A
Y
Y
E
K
T
R
E
L
R
P
N
Sea Urchin
Strong. purpuratus
XP_001192247
485
55478
S228
Q
L
A
E
K
I
R
S
P
K
P
I
E
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850285
733
81796
R225
Q
L
L
Q
N
I
I
R
S
T
E
L
H
F
P
Baker's Yeast
Sacchar. cerevisiae
P53104
897
101699
R281
E
L
F
K
K
I
K
R
A
N
D
V
I
T
F
Red Bread Mold
Neurospora crassa
Q7RX99
932
102644
S285
E
L
L
R
K
I
E
S
S
G
D
V
I
K
F
Conservation
Percent
Protein Identity:
100
99.1
73.7
75.3
N.A.
94
93.6
N.A.
N.A.
78.1
72.8
71.1
N.A.
40.1
44.1
23.8
48
Protein Similarity:
100
99.5
77.9
79
N.A.
97.6
96.4
N.A.
N.A.
90
87.2
84.7
N.A.
57.6
64.3
37.1
64.5
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
86.6
73.3
80
N.A.
46.6
66.6
13.3
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
86.6
N.A.
53.3
73.3
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.7
24.8
23.8
Protein Similarity:
N.A.
N.A.
N.A.
41.6
36.3
35
P-Site Identity:
N.A.
N.A.
N.A.
20
26.6
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
46.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
0
0
0
13
0
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
7
0
13
0
0
0
0
% D
% Glu:
82
0
57
69
0
0
13
0
7
7
13
0
63
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
13
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% H
% Ile:
0
0
7
0
0
94
7
0
0
0
0
69
13
7
0
% I
% Lys:
0
0
7
7
82
0
13
13
0
13
0
0
7
7
0
% K
% Leu:
0
100
19
7
0
0
7
0
0
0
0
13
0
69
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
38
7
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
13
0
0
7
82
% P
% Gln:
19
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
7
0
63
13
0
63
0
0
7
0
0
% R
% Ser:
0
0
0
0
0
0
0
69
13
0
7
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
7
7
0
7
7
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
38
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _