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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ULK3 All Species: 36.97
Human Site: S277 Identified Species: 54.22
UniProt: Q6PHR2 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PHR2 NP_001092906.1 472 53444 S277 V D L E H M P S G E S L G R A
Chimpanzee Pan troglodytes XP_510672 472 53351 S277 V D L E H M P S G E S L G R A
Rhesus Macaque Macaca mulatta XP_001098063 525 59288 S277 V D L E H M P S R E S L D R A
Dog Lupus familis XP_544776 581 65042 S386 V D L E H M P S G E S L A R A
Cat Felis silvestris
Mouse Mus musculus Q3U3Q1 472 53553 S277 V D L E H M P S G E S L A Q A
Rat Rattus norvegicus XP_001077085 474 53543 S277 V D L E H M P S G E S L A Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJH6 468 53047 G277 V D M E H M P G P E S F C K A
Frog Xenopus laevis Q4V7Q6 468 53109 S276 V D L E H M P S A E T L E K A
Zebra Danio Brachydanio rerio NP_001082941 468 53407 S274 V D L E H M P S A E S L P K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_731331 520 59745 T272 L D L K T F P T E H T L Q K A
Honey Bee Apis mellifera XP_396911 480 55199 T271 L D L A H A P T K E N Y D K A
Nematode Worm Caenorhab. elegans Q23023 856 94874 T590 F I I K N Q T T C S T S S T S
Sea Urchin Strong. purpuratus XP_001192247 485 55478 N289 L D K A V S I N T K R L E T L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_850285 733 81796 L496 T S H G S L D L G D A F E Q P
Baker's Yeast Sacchar. cerevisiae P53104 897 101699 G372 S P N S N L A G H Q S M A D N
Red Bread Mold Neurospora crassa Q7RX99 932 102644 R421 Q I P P R E D R L S Y S P R K
Conservation
Percent
Protein Identity: 100 99.1 73.7 75.3 N.A. 94 93.6 N.A. N.A. 78.1 72.8 71.1 N.A. 40.1 44.1 23.8 48
Protein Similarity: 100 99.5 77.9 79 N.A. 97.6 96.4 N.A. N.A. 90 87.2 84.7 N.A. 57.6 64.3 37.1 64.5
P-Site Identity: 100 100 86.6 93.3 N.A. 86.6 86.6 N.A. N.A. 60 73.3 80 N.A. 33.3 40 0 13.3
P-Site Similarity: 100 100 86.6 93.3 N.A. 93.3 93.3 N.A. N.A. 73.3 86.6 86.6 N.A. 66.6 66.6 40 33.3
Percent
Protein Identity: N.A. N.A. N.A. 26.7 24.8 23.8
Protein Similarity: N.A. N.A. N.A. 41.6 36.3 35
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 33.3 33.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 13 0 7 7 0 13 0 7 0 25 0 69 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % C
% Asp: 0 75 0 0 0 0 13 0 0 7 0 0 13 7 0 % D
% Glu: 0 0 0 57 0 7 0 0 7 63 0 0 19 0 0 % E
% Phe: 7 0 0 0 0 7 0 0 0 0 0 13 0 0 0 % F
% Gly: 0 0 0 7 0 0 0 13 38 0 0 0 13 0 0 % G
% His: 0 0 7 0 63 0 0 0 7 7 0 0 0 0 0 % H
% Ile: 0 13 7 0 0 0 7 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 7 13 0 0 0 0 7 7 0 0 0 32 7 % K
% Leu: 19 0 63 0 0 13 0 7 7 0 0 63 0 0 7 % L
% Met: 0 0 7 0 0 57 0 0 0 0 0 7 0 0 0 % M
% Asn: 0 0 7 0 13 0 0 7 0 0 7 0 0 0 7 % N
% Pro: 0 7 7 7 0 0 69 0 7 0 0 0 13 0 7 % P
% Gln: 7 0 0 0 0 7 0 0 0 7 0 0 7 19 0 % Q
% Arg: 0 0 0 0 7 0 0 7 7 0 7 0 0 32 0 % R
% Ser: 7 7 0 7 7 7 0 50 0 13 57 13 7 0 7 % S
% Thr: 7 0 0 0 7 0 7 19 7 0 19 0 0 13 0 % T
% Val: 57 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 7 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _