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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ULK3 All Species: 38.18
Human Site: S280 Identified Species: 56
UniProt: Q6PHR2 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PHR2 NP_001092906.1 472 53444 S280 E H M P S G E S L G R A T A L
Chimpanzee Pan troglodytes XP_510672 472 53351 S280 E H M P S G E S L G R A T A L
Rhesus Macaque Macaca mulatta XP_001098063 525 59288 S280 E H M P S R E S L D R A T T L
Dog Lupus familis XP_544776 581 65042 S389 E H M P S G E S L A R A T A L
Cat Felis silvestris
Mouse Mus musculus Q3U3Q1 472 53553 S280 E H M P S G E S L A Q A R A L
Rat Rattus norvegicus XP_001077085 474 53543 S280 E H M P S G E S L A Q A T A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJH6 468 53047 S280 E H M P G P E S F C K A T N L
Frog Xenopus laevis Q4V7Q6 468 53109 T279 E H M P S A E T L E K A T R L
Zebra Danio Brachydanio rerio NP_001082941 468 53407 S277 E H M P S A E S L P K A K A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_731331 520 59745 T275 K T F P T E H T L Q K A I D L
Honey Bee Apis mellifera XP_396911 480 55199 N274 A H A P T K E N Y D K A I E L
Nematode Worm Caenorhab. elegans Q23023 856 94874 T593 K N Q T T C S T S S T S S S V
Sea Urchin Strong. purpuratus XP_001192247 485 55478 R292 A V S I N T K R L E T L R T T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_850285 733 81796 A499 G S L D L G D A F E Q P S T H
Baker's Yeast Sacchar. cerevisiae P53104 897 101699 S375 S N L A G H Q S M A D N P A E
Red Bread Mold Neurospora crassa Q7RX99 932 102644 Y424 P R E D R L S Y S P R K E A A
Conservation
Percent
Protein Identity: 100 99.1 73.7 75.3 N.A. 94 93.6 N.A. N.A. 78.1 72.8 71.1 N.A. 40.1 44.1 23.8 48
Protein Similarity: 100 99.5 77.9 79 N.A. 97.6 96.4 N.A. N.A. 90 87.2 84.7 N.A. 57.6 64.3 37.1 64.5
P-Site Identity: 100 100 80 93.3 N.A. 80 86.6 N.A. N.A. 60 66.6 73.3 N.A. 26.6 33.3 0 6.6
P-Site Similarity: 100 100 80 93.3 N.A. 86.6 93.3 N.A. N.A. 66.6 80 80 N.A. 53.3 53.3 53.3 20
Percent
Protein Identity: N.A. N.A. N.A. 26.7 24.8 23.8
Protein Similarity: N.A. N.A. N.A. 41.6 36.3 35
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. 40 40 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 7 7 0 13 0 7 0 25 0 69 0 50 7 % A
% Cys: 0 0 0 0 0 7 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 0 0 13 0 0 7 0 0 13 7 0 0 7 0 % D
% Glu: 57 0 7 0 0 7 63 0 0 19 0 0 7 7 7 % E
% Phe: 0 0 7 0 0 0 0 0 13 0 0 0 0 0 0 % F
% Gly: 7 0 0 0 13 38 0 0 0 13 0 0 0 0 0 % G
% His: 0 63 0 0 0 7 7 0 0 0 0 0 0 0 7 % H
% Ile: 0 0 0 7 0 0 0 0 0 0 0 0 13 0 0 % I
% Lys: 13 0 0 0 0 7 7 0 0 0 32 7 7 0 0 % K
% Leu: 0 0 13 0 7 7 0 0 63 0 0 7 0 0 69 % L
% Met: 0 0 57 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 13 0 0 7 0 0 7 0 0 0 7 0 7 0 % N
% Pro: 7 0 0 69 0 7 0 0 0 13 0 7 7 0 0 % P
% Gln: 0 0 7 0 0 0 7 0 0 7 19 0 0 0 0 % Q
% Arg: 0 7 0 0 7 7 0 7 0 0 32 0 13 7 0 % R
% Ser: 7 7 7 0 50 0 13 57 13 7 0 7 13 7 0 % S
% Thr: 0 7 0 7 19 7 0 19 0 0 13 0 44 19 7 % T
% Val: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _