Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ULK3 All Species: 23.94
Human Site: S462 Identified Species: 35.11
UniProt: Q6PHR2 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PHR2 NP_001092906.1 472 53444 S462 T L D K E G L S E S V R S S C
Chimpanzee Pan troglodytes XP_510672 472 53351 S462 T L D K E G L S E S V R S S C
Rhesus Macaque Macaca mulatta XP_001098063 525 59288 E500 S P Q W Q P L E A V V V A A A
Dog Lupus familis XP_544776 581 65042 S571 T L D K E G L S E S V R T S C
Cat Felis silvestris
Mouse Mus musculus Q3U3Q1 472 53553 S462 S L D K E G L S E S V R S S C
Rat Rattus norvegicus XP_001077085 474 53543 S462 S L D K E G L S E S V R S C K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJH6 468 53047 A458 S M G K E A L A D S V R S S C
Frog Xenopus laevis Q4V7Q6 468 53109 S458 S L G Q E V L S E S V R N S C
Zebra Danio Brachydanio rerio NP_001082941 468 53407 E459 L K K D A A A E S V R S S C C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_731331 520 59745 S501 T I T F Q G W S K P P L I F F
Honey Bee Apis mellifera XP_396911 480 55199 R469 D I E E S A Q R G S D A S E Q
Nematode Worm Caenorhab. elegans Q23023 856 94874 R847 K R L R I L E R Q G F V A A V
Sea Urchin Strong. purpuratus XP_001192247 485 55478 Y472 R A E V L K Q Y I E V C Q I L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_850285 733 81796 A718 Q S H R R S S A G Q M Q G S S
Baker's Yeast Sacchar. cerevisiae P53104 897 101699 E778 V A E N Q T L E E K G S S E E
Red Bread Mold Neurospora crassa Q7RX99 932 102644 H811 H P S H P N N H A N D S T A L
Conservation
Percent
Protein Identity: 100 99.1 73.7 75.3 N.A. 94 93.6 N.A. N.A. 78.1 72.8 71.1 N.A. 40.1 44.1 23.8 48
Protein Similarity: 100 99.5 77.9 79 N.A. 97.6 96.4 N.A. N.A. 90 87.2 84.7 N.A. 57.6 64.3 37.1 64.5
P-Site Identity: 100 100 13.3 93.3 N.A. 93.3 80 N.A. N.A. 60 66.6 13.3 N.A. 20 13.3 0 6.6
P-Site Similarity: 100 100 40 100 N.A. 100 86.6 N.A. N.A. 86.6 86.6 13.3 N.A. 40 33.3 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 26.7 24.8 23.8
Protein Similarity: N.A. N.A. N.A. 41.6 36.3 35
P-Site Identity: N.A. N.A. N.A. 6.6 20 0
P-Site Similarity: N.A. N.A. N.A. 33.3 33.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 7 19 7 13 13 0 0 7 13 19 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 13 44 % C
% Asp: 7 0 32 7 0 0 0 0 7 0 13 0 0 0 0 % D
% Glu: 0 0 19 7 44 0 7 19 44 7 0 0 0 13 7 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 7 0 0 7 7 % F
% Gly: 0 0 13 0 0 38 0 0 13 7 7 0 7 0 0 % G
% His: 7 0 7 7 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 13 0 0 7 0 0 0 7 0 0 0 7 7 0 % I
% Lys: 7 7 7 38 0 7 0 0 7 7 0 0 0 0 7 % K
% Leu: 7 38 7 0 7 7 57 0 0 0 0 7 0 0 13 % L
% Met: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 7 0 7 7 0 0 7 0 0 7 0 0 % N
% Pro: 0 13 0 0 7 7 0 0 0 7 7 0 0 0 0 % P
% Gln: 7 0 7 7 19 0 13 0 7 7 0 7 7 0 7 % Q
% Arg: 7 7 0 13 7 0 0 13 0 0 7 44 0 0 0 % R
% Ser: 32 7 7 0 7 7 7 44 7 50 0 19 50 44 7 % S
% Thr: 25 0 7 0 0 7 0 0 0 0 0 0 13 0 0 % T
% Val: 7 0 0 7 0 7 0 0 0 13 57 13 0 0 7 % V
% Trp: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _