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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SHQ1 All Species: 18.18
Human Site: Y251 Identified Species: 40
UniProt: Q6PI26 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PI26 NP_060600.2 577 65125 Y251 S F S E E E K Y Q L R K F V N
Chimpanzee Pan troglodytes XP_001141951 577 65137 Y251 S F S E E E K Y Q L R K F V N
Rhesus Macaque Macaca mulatta XP_001082636 577 65185 Y251 S F S E E E K Y Q L R K F V N
Dog Lupus familis XP_863226 576 64705 Y250 S F S E E E K Y Q L R K F V N
Cat Felis silvestris
Mouse Mus musculus Q7TMX5 569 63440 Y253 S F S E E E K Y Q L R K F V N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516170 329 37576 I17 Q D P D F L T I T I S V P Y A
Chicken Gallus gallus XP_414429 608 68947 E249 I F S D E E R E Q L R K F T N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A1L1R0 585 67481 E242 T F T E E E R E Q M R R F T N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623827 406 47617 L94 N L D M I S T L L A P P K K K
Nematode Worm Caenorhab. elegans Q9TYM6 431 49521 E119 V E E M D D S E D D D E G D G
Sea Urchin Strong. purpuratus XP_796182 622 69915 E258 G F T E D E K E L M V K L P R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 94.9 82.6 N.A. 75.5 N.A. N.A. 42.6 59.2 N.A. 46.8 N.A. N.A. 29.9 28.7 34.8
Protein Similarity: 100 99.6 97.2 87.1 N.A. 84.4 N.A. N.A. 48.7 73.5 N.A. 62.7 N.A. N.A. 46.6 43.6 53.5
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 0 66.6 N.A. 53.3 N.A. N.A. 0 0 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 13.3 80 N.A. 86.6 N.A. N.A. 6.6 20 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 19 19 10 0 0 10 10 10 0 0 10 0 % D
% Glu: 0 10 10 64 64 73 0 37 0 0 0 10 0 0 0 % E
% Phe: 0 73 0 0 10 0 0 0 0 0 0 0 64 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 10 0 0 10 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 55 0 0 0 0 64 10 10 10 % K
% Leu: 0 10 0 0 0 10 0 10 19 55 0 0 10 0 0 % L
% Met: 0 0 0 19 0 0 0 0 0 19 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 64 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 10 10 10 10 0 % P
% Gln: 10 0 0 0 0 0 0 0 64 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 19 0 0 0 64 10 0 0 10 % R
% Ser: 46 0 55 0 0 10 10 0 0 0 10 0 0 0 0 % S
% Thr: 10 0 19 0 0 0 19 0 10 0 0 0 0 19 0 % T
% Val: 10 0 0 0 0 0 0 0 0 0 10 10 0 46 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 46 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _