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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHQ1
All Species:
26.67
Human Site:
Y376
Identified Species:
58.67
UniProt:
Q6PI26
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PI26
NP_060600.2
577
65125
Y376
F
Q
E
N
D
P
A
Y
I
L
N
D
L
Y
I
Chimpanzee
Pan troglodytes
XP_001141951
577
65137
Y376
F
Q
E
N
D
P
A
Y
I
L
N
D
L
Y
I
Rhesus Macaque
Macaca mulatta
XP_001082636
577
65185
Y376
F
Q
E
N
D
P
A
Y
I
L
N
D
L
Y
I
Dog
Lupus familis
XP_863226
576
64705
Y375
F
Q
E
N
D
P
A
Y
I
L
N
D
L
Y
I
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMX5
569
63440
E373
D
V
H
K
V
F
Q
E
N
D
P
A
Y
I
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516170
329
37576
T137
Q
I
P
Y
E
A
A
T
K
N
T
L
N
T
Q
Chicken
Gallus gallus
XP_414429
608
68947
Y374
F
R
E
S
D
P
A
Y
I
L
N
D
L
F
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L1R0
585
67481
Y367
F
R
E
N
D
P
A
Y
I
L
N
D
L
Y
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623827
406
47617
V214
H
K
L
L
L
G
L
V
D
I
L
F
A
S
C
Nematode Worm
Caenorhab. elegans
Q9TYM6
431
49521
D239
E
D
R
T
K
L
K
D
L
K
K
S
K
T
S
Sea Urchin
Strong. purpuratus
XP_796182
622
69915
Y383
L
S
N
D
E
P
R
Y
I
L
N
D
L
Y
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
94.9
82.6
N.A.
75.5
N.A.
N.A.
42.6
59.2
N.A.
46.8
N.A.
N.A.
29.9
28.7
34.8
Protein Similarity:
100
99.6
97.2
87.1
N.A.
84.4
N.A.
N.A.
48.7
73.5
N.A.
62.7
N.A.
N.A.
46.6
43.6
53.5
P-Site Identity:
100
100
100
100
N.A.
0
N.A.
N.A.
6.6
80
N.A.
93.3
N.A.
N.A.
0
0
60
P-Site Similarity:
100
100
100
100
N.A.
6.6
N.A.
N.A.
13.3
100
N.A.
100
N.A.
N.A.
13.3
6.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
64
0
0
0
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
10
0
10
55
0
0
10
10
10
0
64
0
0
0
% D
% Glu:
10
0
55
0
19
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
55
0
0
0
0
10
0
0
0
0
0
10
0
10
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
64
10
0
0
0
10
64
% I
% Lys:
0
10
0
10
10
0
10
0
10
10
10
0
10
0
0
% K
% Leu:
10
0
10
10
10
10
10
0
10
64
10
10
64
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
46
0
0
0
0
10
10
64
0
10
0
0
% N
% Pro:
0
0
10
0
0
64
0
0
0
0
10
0
0
0
0
% P
% Gln:
10
37
0
0
0
0
10
0
0
0
0
0
0
0
10
% Q
% Arg:
0
19
10
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
10
0
0
0
0
0
0
0
10
0
10
10
% S
% Thr:
0
0
0
10
0
0
0
10
0
0
10
0
0
19
0
% T
% Val:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
64
0
0
0
0
10
55
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _