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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD18
All Species:
13.64
Human Site:
S245
Identified Species:
60
UniProt:
Q6PI47
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PI47
NP_689600.2
426
46739
S245
E
E
R
P
L
L
G
S
L
R
H
M
A
P
I
Chimpanzee
Pan troglodytes
XP_516016
426
46706
S245
E
E
Q
P
L
L
G
S
L
R
H
M
A
P
I
Rhesus Macaque
Macaca mulatta
XP_001092190
426
46660
S245
E
E
R
P
L
L
G
S
L
R
H
M
A
P
I
Dog
Lupus familis
XP_545585
549
59163
S245
E
E
R
P
L
L
G
S
L
R
H
M
A
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519321
396
44413
I217
V
V
P
A
N
K
Q
I
N
S
F
R
V
F
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DG99
237
27614
I58
D
A
Q
G
N
Y
F
I
D
R
D
G
T
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.7
60.1
N.A.
N.A.
N.A.
N.A.
21.6
N.A.
N.A.
20.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
96.9
65.9
N.A.
N.A.
N.A.
N.A.
37
N.A.
N.A.
31.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
93.3
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
17
0
0
0
0
0
0
0
0
67
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
0
0
0
0
0
0
17
0
17
0
0
0
0
% D
% Glu:
67
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
17
0
0
0
17
0
0
17
17
% F
% Gly:
0
0
0
17
0
0
67
0
0
0
0
17
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
67
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
50
% I
% Lys:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
67
67
0
0
67
0
0
0
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% M
% Asn:
0
0
0
0
34
0
0
0
17
0
0
0
0
0
0
% N
% Pro:
0
0
17
67
0
0
0
0
0
0
0
0
0
67
0
% P
% Gln:
0
0
34
0
0
0
17
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
50
0
0
0
0
0
0
84
0
17
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
67
0
17
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% T
% Val:
17
17
0
0
0
0
0
0
0
0
0
0
17
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _