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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DARS2
All Species:
25.76
Human Site:
S450
Identified Species:
56.67
UniProt:
Q6PI48
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PI48
NP_060592.2
645
73563
S450
G
E
H
N
K
A
C
S
L
L
G
K
L
R
L
Chimpanzee
Pan troglodytes
XP_524974
645
73576
S450
G
E
H
N
K
A
C
S
L
L
G
K
L
R
L
Rhesus Macaque
Macaca mulatta
XP_001101931
640
72841
S445
G
E
H
N
K
A
C
S
L
L
G
K
L
R
L
Dog
Lupus familis
XP_547457
652
73693
S448
G
E
H
K
K
A
C
S
V
L
G
K
L
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIP0
653
74084
S449
G
E
H
E
K
A
C
S
L
L
G
K
L
R
L
Rat
Rattus norvegicus
Q3KRD0
652
73934
S449
G
Q
H
E
K
A
C
S
L
L
G
K
L
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515219
880
98346
S686
G
E
H
T
N
S
C
S
L
L
G
K
L
R
L
Chicken
Gallus gallus
XP_422251
561
62636
L248
R
L
E
S
A
D
L
L
E
A
A
G
M
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_699804
660
74296
P471
G
P
R
E
N
V
R
P
L
L
G
K
L
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724018
1082
121501
E800
G
S
K
V
E
T
R
E
L
L
G
R
I
R
L
Honey Bee
Apis mellifera
XP_001121020
577
66986
L395
E
K
V
D
T
Q
L
L
L
G
K
I
R
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
95
85.4
N.A.
84.5
84.1
N.A.
57
34.4
N.A.
61.3
N.A.
30.3
45.1
N.A.
N.A.
Protein Similarity:
100
99.5
97.3
90.9
N.A.
90.9
91.2
N.A.
65.9
47.7
N.A.
75.6
N.A.
40.9
60.7
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
80
6.6
N.A.
53.3
N.A.
40
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
20
N.A.
53.3
N.A.
60
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
55
0
0
0
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
64
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
55
10
28
10
0
0
10
10
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
82
0
0
0
0
0
0
0
0
10
82
10
0
0
0
% G
% His:
0
0
64
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% I
% Lys:
0
10
10
10
55
0
0
0
0
0
10
73
0
0
0
% K
% Leu:
0
10
0
0
0
0
19
19
82
82
0
0
73
10
91
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
28
19
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
10
0
0
0
19
0
0
0
0
10
10
82
0
% R
% Ser:
0
10
0
10
0
10
0
64
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
10
0
10
0
0
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _