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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DARS2 All Species: 34.55
Human Site: T335 Identified Species: 76
UniProt: Q6PI48 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PI48 NP_060592.2 645 73563 T335 Y G T D K P D T R F G M K I I
Chimpanzee Pan troglodytes XP_524974 645 73576 T335 Y G T D K P D T R F G M K I I
Rhesus Macaque Macaca mulatta XP_001101931 640 72841 T330 Y G T D K P D T R F G M K I I
Dog Lupus familis XP_547457 652 73693 T333 Y G T D K P D T R F G M K I V
Cat Felis silvestris
Mouse Mus musculus Q8BIP0 653 74084 T334 Y G T D K P D T R F G M K I V
Rat Rattus norvegicus Q3KRD0 652 73934 T334 Y G T D K P D T R F G M K I V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515219 880 98346 T571 Y G L D K P D T R F G M K I L
Chicken Gallus gallus XP_422251 561 62636 K275 D F P L F L P K E E N P S E L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_699804 660 74296 T356 Y G V D K P D T R F G M K L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_724018 1082 121501 T690 Y G N D K P D T R F G F L L N
Honey Bee Apis mellifera XP_001121020 577 66986 C291 E L T I P F K C M K Y D N A M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 95 85.4 N.A. 84.5 84.1 N.A. 57 34.4 N.A. 61.3 N.A. 30.3 45.1 N.A. N.A.
Protein Similarity: 100 99.5 97.3 90.9 N.A. 90.9 91.2 N.A. 65.9 47.7 N.A. 75.6 N.A. 40.9 60.7 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 86.6 0 N.A. 80 N.A. 66.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 6.6 N.A. 93.3 N.A. 73.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 82 0 0 82 0 0 0 0 10 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 10 10 0 0 0 10 0 % E
% Phe: 0 10 0 0 10 10 0 0 0 82 0 10 0 0 0 % F
% Gly: 0 82 0 0 0 0 0 0 0 0 82 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 64 28 % I
% Lys: 0 0 0 0 82 0 10 10 0 10 0 0 73 0 0 % K
% Leu: 0 10 10 10 0 10 0 0 0 0 0 0 10 19 19 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 73 0 0 10 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 10 0 10 0 10 % N
% Pro: 0 0 10 0 10 82 10 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 82 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % S
% Thr: 0 0 64 0 0 0 0 82 0 0 0 0 0 0 0 % T
% Val: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 82 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _