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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM65
All Species:
14.55
Human Site:
T56
Identified Species:
40
UniProt:
Q6PI78
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PI78
NP_919267.2
240
25498
T56
G
G
P
R
R
L
G
T
H
P
K
K
E
P
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101526
248
26089
T64
G
G
P
R
R
L
G
T
H
P
K
K
E
P
M
Dog
Lupus familis
XP_851731
242
25535
T58
G
G
S
R
A
L
G
T
H
P
K
K
E
P
M
Cat
Felis silvestris
Mouse
Mus musculus
Q4VAE3
234
24900
T50
G
G
P
R
L
L
G
T
H
P
K
K
E
P
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511596
169
18063
Chicken
Gallus gallus
NP_001026678
176
18861
D12
N
T
A
Q
G
A
R
D
F
I
Y
S
L
H
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001122284
212
23051
T46
Q
L
E
L
P
N
Q
T
R
E
F
V
Y
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036408
233
26087
N47
S
S
P
F
T
C
R
N
Y
S
K
F
S
T
H
Honey Bee
Apis mellifera
XP_623613
262
29796
T52
I
N
F
S
N
S
L
T
K
D
K
I
K
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.1
94.2
N.A.
92
N.A.
N.A.
54.1
64.1
N.A.
56.2
N.A.
36.6
29.7
N.A.
N.A.
Protein Similarity:
100
N.A.
95.1
95.4
N.A.
94.1
N.A.
N.A.
64.5
70
N.A.
67.5
N.A.
53.3
45
N.A.
N.A.
P-Site Identity:
100
N.A.
100
86.6
N.A.
93.3
N.A.
N.A.
0
0
N.A.
6.6
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
86.6
N.A.
93.3
N.A.
N.A.
0
6.6
N.A.
13.3
N.A.
20
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
12
12
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
12
0
0
0
0
0
% D
% Glu:
0
0
12
0
0
0
0
0
0
12
0
0
45
0
0
% E
% Phe:
0
0
12
12
0
0
0
0
12
0
12
12
0
0
0
% F
% Gly:
45
45
0
0
12
0
45
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
45
0
0
0
0
12
12
% H
% Ile:
12
0
0
0
0
0
0
0
0
12
0
12
0
0
12
% I
% Lys:
0
0
0
0
0
0
0
0
12
0
67
45
12
12
0
% K
% Leu:
0
12
0
12
12
45
12
0
0
0
0
0
12
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% M
% Asn:
12
12
0
0
12
12
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
45
0
12
0
0
0
0
45
0
0
0
45
0
% P
% Gln:
12
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
45
23
0
23
0
12
0
0
0
0
0
0
% R
% Ser:
12
12
12
12
0
12
0
0
0
12
0
12
12
12
12
% S
% Thr:
0
12
0
0
12
0
0
67
0
0
0
0
0
12
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
12
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _