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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INO80C All Species: 23.94
Human Site: S46 Identified Species: 37.62
UniProt: Q6PI98 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PI98 NP_919257.2 192 20643 S46 A S K K K K A S A S S F A Q G
Chimpanzee Pan troglodytes XP_001135553 210 22556 S46 A S K K K K A S A S S F A Q T
Rhesus Macaque Macaca mulatta XP_001104744 192 20647 S46 A S K K K K V S A S S F A Q G
Dog Lupus familis XP_547606 246 26199 S100 A S K K K K V S A A S F T Q G
Cat Felis silvestris
Mouse Mus musculus Q8BHA0 191 20387 S45 A S K K K K L S A S G F A Q G
Rat Rattus norvegicus Q5BJY3 191 20406 S45 A S K K K K L S A S G F A Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513039 175 19236 S35 L W F L S K R S G I S I E S V
Chicken Gallus gallus XP_419041 185 19512 S44 K V A A S S G S Q S A G G E V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002108 210 22453 P50 S P A T H T T P L T N N I I N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_727280 110 12413
Honey Bee Apis mellifera XP_624857 271 31350 K71 N I K H F M E K H N S K F N Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785838 291 30508 S96 S S P A A T T S T N A T M A T
Poplar Tree Populus trichocarpa XP_002323030 123 14393
Maize Zea mays NP_001147223 125 14698
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32617 166 18514 G26 N N N N N D G G D E R L L F L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.4 98.4 74.3 N.A. 90.6 91.1 N.A. 65 73.4 N.A. 53.8 N.A. 28.1 29.8 N.A. 35.7
Protein Similarity: 100 91.4 99.4 75.6 N.A. 95.3 94.7 N.A. 72.9 81.2 N.A. 67.6 N.A. 42.1 43.9 N.A. 45.7
P-Site Identity: 100 93.3 93.3 80 N.A. 86.6 86.6 N.A. 20 13.3 N.A. 0 N.A. 0 13.3 N.A. 13.3
P-Site Similarity: 100 93.3 93.3 86.6 N.A. 86.6 86.6 N.A. 20 26.6 N.A. 20 N.A. 0 20 N.A. 33.3
Percent
Protein Identity: 25.5 27.6 N.A. N.A. 23.9 N.A.
Protein Similarity: 41.6 39.5 N.A. N.A. 40.6 N.A.
P-Site Identity: 0 0 N.A. N.A. 0 N.A.
P-Site Similarity: 0 0 N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 0 14 14 7 0 14 0 40 7 14 0 34 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 7 0 0 7 0 0 7 7 0 % E
% Phe: 0 0 7 0 7 0 0 0 0 0 0 40 7 7 0 % F
% Gly: 0 0 0 0 0 0 14 7 7 0 14 7 7 0 34 % G
% His: 0 0 0 7 7 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 7 0 7 7 7 0 % I
% Lys: 7 0 47 40 40 47 0 7 0 0 0 7 0 0 0 % K
% Leu: 7 0 0 7 0 0 14 0 7 0 0 7 7 0 7 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 0 7 0 0 % M
% Asn: 14 7 7 7 7 0 0 0 0 14 7 7 0 7 7 % N
% Pro: 0 7 7 0 0 0 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 0 0 0 0 40 0 % Q
% Arg: 0 0 0 0 0 0 7 0 0 0 7 0 0 0 0 % R
% Ser: 14 47 0 0 14 7 0 60 0 40 40 0 0 7 0 % S
% Thr: 0 0 0 7 0 14 14 0 7 7 0 7 7 0 14 % T
% Val: 0 7 0 0 0 0 14 0 0 0 0 0 0 0 14 % V
% Trp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _