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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INO80C All Species: 18.48
Human Site: T71 Identified Species: 29.05
UniProt: Q6PI98 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PI98 NP_919257.2 192 20643 T71 M V P S E F S T G P V E K A A
Chimpanzee Pan troglodytes XP_001135553 210 22556 G71 P P Q P R G N G I S M E A M S
Rhesus Macaque Macaca mulatta XP_001104744 192 20647 T71 V V P S E F S T G P V E K A A
Dog Lupus familis XP_547606 246 26199 T125 M V T S D F S T G P M E K A A
Cat Felis silvestris
Mouse Mus musculus Q8BHA0 191 20387 S70 M A S S E L S S G P V E K A A
Rat Rattus norvegicus Q5BJY3 191 20406 S70 M A S S E L S S G P V E K A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513039 175 19236 T60 G A G P V D A T A K P L P F K
Chicken Gallus gallus XP_419041 185 19512 T69 S S T G S V E T A V K P L P F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002108 210 22453 V75 L S T A Q A Q V A P V E G T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_727280 110 12413
Honey Bee Apis mellifera XP_624857 271 31350 L96 L L C H H A I L C L I E P S K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785838 291 30508 S121 V P K E D V P S K P I V S T Q
Poplar Tree Populus trichocarpa XP_002323030 123 14393 A8 M E A E L I N A E L V L P T H
Maize Zea mays NP_001147223 125 14698 E10 E S E V V R M E M V L A P T L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32617 166 18514 A51 F P S R F K S A H Y K K P T R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.4 98.4 74.3 N.A. 90.6 91.1 N.A. 65 73.4 N.A. 53.8 N.A. 28.1 29.8 N.A. 35.7
Protein Similarity: 100 91.4 99.4 75.6 N.A. 95.3 94.7 N.A. 72.9 81.2 N.A. 67.6 N.A. 42.1 43.9 N.A. 45.7
P-Site Identity: 100 6.6 93.3 80 N.A. 73.3 73.3 N.A. 6.6 6.6 N.A. 20 N.A. 0 6.6 N.A. 6.6
P-Site Similarity: 100 26.6 100 93.3 N.A. 80 80 N.A. 13.3 6.6 N.A. 46.6 N.A. 0 33.3 N.A. 33.3
Percent
Protein Identity: 25.5 27.6 N.A. N.A. 23.9 N.A.
Protein Similarity: 41.6 39.5 N.A. N.A. 40.6 N.A.
P-Site Identity: 13.3 0 N.A. N.A. 6.6 N.A.
P-Site Similarity: 20 6.6 N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 7 7 0 14 7 14 20 0 0 7 7 34 34 % A
% Cys: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 14 7 0 0 0 0 0 0 0 0 0 % D
% Glu: 7 7 7 14 27 0 7 7 7 0 0 54 0 0 0 % E
% Phe: 7 0 0 0 7 20 0 0 0 0 0 0 0 7 7 % F
% Gly: 7 0 7 7 0 7 0 7 34 0 0 0 7 0 0 % G
% His: 0 0 0 7 7 0 0 0 7 0 0 0 0 0 7 % H
% Ile: 0 0 0 0 0 7 7 0 7 0 14 0 0 0 0 % I
% Lys: 0 0 7 0 0 7 0 0 7 7 14 7 34 0 14 % K
% Leu: 14 7 0 0 7 14 0 7 0 14 7 14 7 0 7 % L
% Met: 34 0 0 0 0 0 7 0 7 0 14 0 0 7 0 % M
% Asn: 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 % N
% Pro: 7 20 14 14 0 0 7 0 0 47 7 7 34 7 0 % P
% Gln: 0 0 7 0 7 0 7 0 0 0 0 0 0 0 7 % Q
% Arg: 0 0 0 7 7 7 0 0 0 0 0 0 0 0 7 % R
% Ser: 7 20 20 34 7 0 40 20 0 7 0 0 7 7 14 % S
% Thr: 0 0 20 0 0 0 0 34 0 0 0 0 0 34 0 % T
% Val: 14 20 0 7 14 14 0 7 0 14 40 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _