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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INO80C All Species: 34.55
Human Site: Y169 Identified Species: 54.29
UniProt: Q6PI98 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PI98 NP_919257.2 192 20643 Y169 S T I E E F S Y I R R L P S D
Chimpanzee Pan troglodytes XP_001135553 210 22556 Y187 S T I E E F S Y I R R L P S D
Rhesus Macaque Macaca mulatta XP_001104744 192 20647 Y169 S T I E E F S Y I R R L P S D
Dog Lupus familis XP_547606 246 26199 Y223 S T I E E F S Y I R R L P S D
Cat Felis silvestris
Mouse Mus musculus Q8BHA0 191 20387 Y168 S T V E E F S Y I R R L P S D
Rat Rattus norvegicus Q5BJY3 191 20406 Y168 S T V E E F S Y I R R L P S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513039 175 19236 I153 T I E E F S Y I R M L P S D V
Chicken Gallus gallus XP_419041 185 19512 Y162 S T I E E F A Y I R M L P S D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002108 210 22453 Y187 A S T E E F S Y I R Q L P T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_727280 110 12413 M88 S A D E Y A S M Q H M P S D I
Honey Bee Apis mellifera XP_624857 271 31350 T248 A T A E E F A T V R S L P M D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785838 291 30508 Q268 S T T E E F A Q L R M F P Q D
Poplar Tree Populus trichocarpa XP_002323030 123 14393 V101 N T D V F K L V R S L P N E H
Maize Zea mays NP_001147223 125 14698 I103 D P E V F K Q I R M L P D E Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32617 166 18514 V144 A E I Y Q L I V K P M A P G V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.4 98.4 74.3 N.A. 90.6 91.1 N.A. 65 73.4 N.A. 53.8 N.A. 28.1 29.8 N.A. 35.7
Protein Similarity: 100 91.4 99.4 75.6 N.A. 95.3 94.7 N.A. 72.9 81.2 N.A. 67.6 N.A. 42.1 43.9 N.A. 45.7
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 6.6 86.6 N.A. 66.6 N.A. 20 53.3 N.A. 53.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 93.3 N.A. 93.3 N.A. 20 73.3 N.A. 66.6
Percent
Protein Identity: 25.5 27.6 N.A. N.A. 23.9 N.A.
Protein Similarity: 41.6 39.5 N.A. N.A. 40.6 N.A.
P-Site Identity: 6.6 0 N.A. N.A. 13.3 N.A.
P-Site Similarity: 13.3 0 N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 7 7 0 0 7 20 0 0 0 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 14 0 0 0 0 0 0 0 0 0 7 14 67 % D
% Glu: 0 7 14 80 67 0 0 0 0 0 0 0 0 14 0 % E
% Phe: 0 0 0 0 20 67 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % H
% Ile: 0 7 40 0 0 0 7 14 54 0 0 0 0 0 7 % I
% Lys: 0 0 0 0 0 14 0 0 7 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 7 7 0 7 0 20 60 0 0 0 % L
% Met: 0 0 0 0 0 0 0 7 0 14 27 0 0 7 0 % M
% Asn: 7 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % N
% Pro: 0 7 0 0 0 0 0 0 0 7 0 27 74 0 0 % P
% Gln: 0 0 0 0 7 0 7 7 7 0 7 0 0 7 0 % Q
% Arg: 0 0 0 0 0 0 0 0 20 67 40 0 0 0 0 % R
% Ser: 60 7 0 0 0 7 54 0 0 7 7 0 14 47 0 % S
% Thr: 7 67 14 0 0 0 0 7 0 0 0 0 0 7 0 % T
% Val: 0 0 14 14 0 0 0 14 7 0 0 0 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 7 0 7 54 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _