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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAGHL
All Species:
9.39
Human Site:
S261
Identified Species:
18.79
UniProt:
Q6PII5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PII5
NP_115680.1
290
31557
S261
R
S
A
S
T
T
P
S
C
G
W
R
E
Y
G
Chimpanzee
Pan troglodytes
XP_001158047
285
30423
S256
R
S
A
S
T
T
P
S
C
G
W
R
E
Y
G
Rhesus Macaque
Macaca mulatta
XP_001087099
282
31296
F254
L
Y
K
E
R
A
R
F
E
Q
A
G
E
P
R
Dog
Lupus familis
XP_547208
383
42155
L345
K
A
A
P
A
E
V
L
E
A
L
C
K
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB32
283
31471
R252
L
E
A
L
C
R
E
R
A
R
F
Q
P
A
V
Rat
Rattus norvegicus
O35952
309
34091
S262
I
G
E
P
T
V
P
S
T
L
A
E
E
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLY2
282
32210
K252
L
R
A
L
R
T
E
K
D
N
F
K
K
P
K
Frog
Xenopus laevis
NP_001090483
300
34052
D265
R
V
L
R
K
E
K
D
E
F
K
K
P
K
D
Zebra Danio
Brachydanio rerio
Q6P963
303
33787
S256
N
G
E
P
T
I
P
S
T
V
A
E
E
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623458
288
32956
S244
K
N
N
P
S
V
P
S
T
I
Q
E
E
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783848
258
28463
A228
N
P
F
M
R
V
G
A
K
S
I
Q
D
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O24496
258
28773
R227
L
E
T
N
P
F
M
R
V
D
K
P
E
I
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82
72.4
49.3
N.A.
63.7
39.8
N.A.
N.A.
53
47
37.9
N.A.
N.A.
39.6
N.A.
39.6
Protein Similarity:
100
84.4
76.2
53
N.A.
69.6
54.6
N.A.
N.A.
60.3
60.3
56.7
N.A.
N.A.
57.2
N.A.
56.2
P-Site Identity:
100
100
6.6
6.6
N.A.
6.6
26.6
N.A.
N.A.
13.3
6.6
26.6
N.A.
N.A.
20
N.A.
0
P-Site Similarity:
100
100
6.6
26.6
N.A.
20
33.3
N.A.
N.A.
33.3
13.3
33.3
N.A.
N.A.
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
42
0
9
9
0
9
9
9
25
0
0
9
0
% A
% Cys:
0
0
0
0
9
0
0
0
17
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
9
9
0
0
9
0
9
% D
% Glu:
0
17
17
9
0
17
17
0
25
0
0
25
59
9
0
% E
% Phe:
0
0
9
0
0
9
0
9
0
9
17
0
0
17
0
% F
% Gly:
0
17
0
0
0
0
9
0
0
17
0
9
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
9
0
0
0
0
9
0
0
0
9
9
0
0
9
0
% I
% Lys:
17
0
9
0
9
0
9
9
9
0
17
17
17
17
9
% K
% Leu:
34
0
9
17
0
0
0
9
0
9
9
0
0
0
9
% L
% Met:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
17
9
9
9
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
9
0
34
9
0
42
0
0
0
0
9
17
17
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
9
17
0
0
9
% Q
% Arg:
25
9
0
9
25
9
9
17
0
9
0
17
0
0
17
% R
% Ser:
0
17
0
17
9
0
0
42
0
9
0
0
0
0
0
% S
% Thr:
0
0
9
0
34
25
0
0
25
0
0
0
0
0
17
% T
% Val:
0
9
0
0
0
25
9
0
9
9
0
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _