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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC23A3
All Species:
4.55
Human Site:
T136
Identified Species:
11.11
UniProt:
Q6PIS1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PIS1
NP_001138361.1
610
64531
T136
K
L
P
R
A
I
Q
T
P
G
N
S
S
L
M
Chimpanzee
Pan troglodytes
XP_516102
493
52279
L57
L
L
A
L
Q
H
V
L
V
M
A
S
L
L
C
Rhesus Macaque
Macaca mulatta
XP_001097078
493
52279
L57
L
L
A
L
Q
H
V
L
V
M
A
S
L
L
C
Dog
Lupus familis
XP_545654
603
63331
L137
Q
T
P
G
N
S
S
L
V
L
R
R
C
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q60850
611
64860
T139
K
L
P
L
T
T
K
T
P
G
N
A
S
L
S
Rat
Rattus norvegicus
Q9WTW8
647
70051
K183
R
A
I
L
S
L
D
K
W
K
C
N
T
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426596
574
60155
L136
L
I
S
G
L
V
Q
L
V
L
G
A
L
G
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339365
609
66281
S159
P
K
W
R
C
P
D
S
S
A
D
P
Q
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185517
690
74101
L223
K
G
P
C
L
D
P
L
P
D
N
A
T
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93039
526
57799
R90
L
Q
S
L
F
G
S
R
L
P
V
V
M
G
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.7
75
79.5
N.A.
78
27
N.A.
N.A.
45.4
N.A.
32.4
N.A.
N.A.
N.A.
N.A.
26.9
Protein Similarity:
100
78
77.3
85
N.A.
84.9
47.9
N.A.
N.A.
55.5
N.A.
51.3
N.A.
N.A.
N.A.
N.A.
46
P-Site Identity:
100
20
20
6.6
N.A.
60
0
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
20
20
13.3
N.A.
73.3
33.3
N.A.
N.A.
33.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
20
0
10
0
0
0
0
10
20
30
0
0
10
% A
% Cys:
0
0
0
10
10
0
0
0
0
0
10
0
10
0
20
% C
% Asp:
0
0
0
0
0
10
20
0
0
10
10
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
20
0
10
0
0
0
20
10
0
0
30
10
% G
% His:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
30
10
0
0
0
0
10
10
0
10
0
0
0
0
0
% K
% Leu:
40
40
0
50
20
10
0
50
10
20
0
0
30
40
0
% L
% Met:
0
0
0
0
0
0
0
0
0
20
0
0
10
0
10
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
30
10
0
0
10
% N
% Pro:
10
0
40
0
0
10
10
0
30
10
0
10
0
0
0
% P
% Gln:
10
10
0
0
20
0
20
0
0
0
0
0
10
0
0
% Q
% Arg:
10
0
0
20
0
0
0
10
0
0
10
10
0
0
0
% R
% Ser:
0
0
20
0
10
10
20
10
10
0
0
30
20
0
10
% S
% Thr:
0
10
0
0
10
10
0
20
0
0
0
0
20
10
0
% T
% Val:
0
0
0
0
0
10
20
0
40
0
10
10
0
10
20
% V
% Trp:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _