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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C1orf228 All Species: 4.85
Human Site: Y182 Identified Species: 17.78
UniProt: Q6PIY5 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PIY5 NP_001139108.1 440 48855 Y182 L V H G N P K Y Q N Q V Y K G
Chimpanzee Pan troglodytes XP_513134 307 33894 I68 R L T T S L R I T Y M T D S C
Rhesus Macaque Macaca mulatta XP_001098567 307 33850 I68 R L T T S L R I T Y V T D S C
Dog Lupus familis XP_532607 307 34044 I69 L T T W L R L I Y M T G S C L
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520782 459 50779 Y182 L V H G N P K Y Q K Q V Y K G
Chicken Gallus gallus
Frog Xenopus laevis NP_001091266 409 46210 V171 T Q E Q A Q V V L E L L A H G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788611 406 44990 S168 E T Q E C A R S L L Q N L A Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.5 68.4 60.9 N.A. N.A. N.A. N.A. 61.2 N.A. 54 N.A. N.A. N.A. N.A. N.A. 51.3
Protein Similarity: 100 69.5 69 65.2 N.A. N.A. N.A. N.A. 77.5 N.A. 70.6 N.A. N.A. N.A. N.A. N.A. 68.1
P-Site Identity: 100 0 0 6.6 N.A. N.A. N.A. N.A. 93.3 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 20 20 6.6 N.A. N.A. N.A. N.A. 93.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 15 0 0 0 0 0 0 15 15 0 % A
% Cys: 0 0 0 0 15 0 0 0 0 0 0 0 0 15 29 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 29 0 0 % D
% Glu: 15 0 15 15 0 0 0 0 0 15 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 29 0 0 0 0 0 0 0 15 0 0 43 % G
% His: 0 0 29 0 0 0 0 0 0 0 0 0 0 15 0 % H
% Ile: 0 0 0 0 0 0 0 43 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 29 0 0 15 0 0 0 29 0 % K
% Leu: 43 29 0 0 15 29 15 0 29 15 15 15 15 0 15 % L
% Met: 0 0 0 0 0 0 0 0 0 15 15 0 0 0 0 % M
% Asn: 0 0 0 0 29 0 0 0 0 15 0 15 0 0 0 % N
% Pro: 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 15 15 15 0 15 0 0 29 0 43 0 0 0 15 % Q
% Arg: 29 0 0 0 0 15 43 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 29 0 0 15 0 0 0 0 15 29 0 % S
% Thr: 15 29 43 29 0 0 0 0 29 0 15 29 0 0 0 % T
% Val: 0 29 0 0 0 0 15 15 0 0 15 29 0 0 0 % V
% Trp: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 29 15 29 0 0 29 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _