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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPSB3 All Species: 35.76
Human Site: S114 Identified Species: 71.52
UniProt: Q6PJ21 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PJ21 NP_543137.2 355 39376 S114 W D D L N K S S A T L L S C D
Chimpanzee Pan troglodytes XP_510737 564 61756 S323 W D D L N K S S A T L L S C D
Rhesus Macaque Macaca mulatta XP_001118630 469 51000 S228 W D D L N K S S A T L L S C D
Dog Lupus familis XP_547191 406 44081 S142 W D D L N K S S A T L L S C D
Cat Felis silvestris
Mouse Mus musculus Q571F5 354 39303 S114 W D D L N K S S A T L L S C D
Rat Rattus norvegicus NP_001100458 391 43585 S149 W D D L N K S S A T L L S C D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513463 309 33751 A77 D D L H K S P A A Q L S C D N
Chicken Gallus gallus XP_414716 355 39468 T115 W D D L N K S T A T L L T C D
Frog Xenopus laevis Q5M9B1 360 40030 T114 W D D C S K S T A T V L S C D
Zebra Danio Brachydanio rerio NP_001116480 358 39880 S114 W D E G S R S S A T L L S C E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122547 298 33975 A66 G Y S Y G T A A V R G N K I L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181890 350 38433 C114 D N A K S N A C C L A K M K T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.4 75 71.6 N.A. 89.3 81.3 N.A. 63.9 81.6 73.3 68.7 N.A. N.A. 34.9 N.A. 35.2
Protein Similarity: 100 62.5 75.4 74.6 N.A. 94.6 86.1 N.A. 70.9 89.3 81.6 79.6 N.A. N.A. 48.7 N.A. 51.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 20 86.6 73.3 66.6 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 33.3 100 93.3 93.3 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 17 17 84 0 9 0 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 9 9 0 0 0 9 75 0 % C
% Asp: 17 84 67 0 0 0 0 0 0 0 0 0 0 9 67 % D
% Glu: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 9 9 0 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 9 9 67 0 0 0 0 0 9 9 9 0 % K
% Leu: 0 0 9 59 0 0 0 0 0 9 75 75 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 9 0 0 59 9 0 0 0 0 0 9 0 0 9 % N
% Pro: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 9 0 0 0 9 0 0 0 0 0 % R
% Ser: 0 0 9 0 25 9 75 59 0 0 0 9 67 0 0 % S
% Thr: 0 0 0 0 0 9 0 17 0 75 0 0 9 0 9 % T
% Val: 0 0 0 0 0 0 0 0 9 0 9 0 0 0 0 % V
% Trp: 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _