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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPSB3 All Species: 36.97
Human Site: S258 Identified Species: 73.94
UniProt: Q6PJ21 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PJ21 NP_543137.2 355 39376 S258 R F Y P M V C S T A A R S S M
Chimpanzee Pan troglodytes XP_510737 564 61756 S467 R F Y P M V C S T A A R S S M
Rhesus Macaque Macaca mulatta XP_001118630 469 51000 S372 R F Y P M V C S T A A R S S M
Dog Lupus familis XP_547191 406 44081 Q286 C A S I T S L Q Y L C C Y R L
Cat Felis silvestris
Mouse Mus musculus Q571F5 354 39303 S258 R F Y P M V C S T A A K S S M
Rat Rattus norvegicus NP_001100458 391 43585 S293 R F Y P M V C S T A A K S S M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513463 309 33751 T221 F Y P M V C S T A A K S S M K
Chicken Gallus gallus XP_414716 355 39468 S259 K F Y P M V C S T A A K S S M
Frog Xenopus laevis Q5M9B1 360 40030 S258 K L F P L V C S T A A K S S M
Zebra Danio Brachydanio rerio NP_001116480 358 39880 S258 H V F P M A C S T A A K S S M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122547 298 33975 T210 V P V S L Q V T C L S V L K S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181890 350 38433 S258 T W Y P I V S S T A A R S S M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.4 75 71.6 N.A. 89.3 81.3 N.A. 63.9 81.6 73.3 68.7 N.A. N.A. 34.9 N.A. 35.2
Protein Similarity: 100 62.5 75.4 74.6 N.A. 94.6 86.1 N.A. 70.9 89.3 81.6 79.6 N.A. N.A. 48.7 N.A. 51.2
P-Site Identity: 100 100 100 0 N.A. 93.3 93.3 N.A. 13.3 86.6 66.6 66.6 N.A. N.A. 0 N.A. 73.3
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 33.3 100 93.3 80 N.A. N.A. 20 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 9 0 0 9 84 75 0 0 0 0 % A
% Cys: 9 0 0 0 0 9 67 0 9 0 9 9 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 50 17 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 17 0 0 0 0 0 0 0 0 0 9 42 0 9 9 % K
% Leu: 0 9 0 0 17 0 9 0 0 17 0 0 9 0 9 % L
% Met: 0 0 0 9 59 0 0 0 0 0 0 0 0 9 75 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 9 75 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 9 0 9 0 0 0 0 0 0 0 % Q
% Arg: 42 0 0 0 0 0 0 0 0 0 0 34 0 9 0 % R
% Ser: 0 0 9 9 0 9 17 75 0 0 9 9 84 75 9 % S
% Thr: 9 0 0 0 9 0 0 17 75 0 0 0 0 0 0 % T
% Val: 9 9 9 0 9 67 9 0 0 0 0 9 0 0 0 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 59 0 0 0 0 0 9 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _