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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPSB3
All Species:
25.15
Human Site:
S318
Identified Species:
50.3
UniProt:
Q6PJ21
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PJ21
NP_543137.2
355
39376
S318
N
K
L
G
W
V
L
S
M
S
C
S
R
R
K
Chimpanzee
Pan troglodytes
XP_510737
564
61756
S527
N
K
L
G
W
V
L
S
M
S
C
S
R
R
K
Rhesus Macaque
Macaca mulatta
XP_001118630
469
51000
S432
N
K
L
G
W
V
L
S
M
S
C
S
R
R
K
Dog
Lupus familis
XP_547191
406
44081
A338
D
R
P
G
S
L
S
A
S
G
S
R
L
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q571F5
354
39303
S318
N
K
L
G
W
V
L
S
M
N
C
N
H
W
K
Rat
Rattus norvegicus
NP_001100458
391
43585
S353
N
K
L
G
W
V
L
S
M
N
C
S
H
W
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513463
309
33751
T273
G
L
K
Q
V
L
Q
T
K
L
G
W
V
L
G
Chicken
Gallus gallus
XP_414716
355
39468
S319
N
K
L
G
W
V
L
S
M
N
Y
S
T
S
K
Frog
Xenopus laevis
Q5M9B1
360
40030
Q318
N
K
L
G
W
V
L
Q
M
G
S
N
R
S
S
Zebra Danio
Brachydanio rerio
NP_001116480
358
39880
S318
S
K
L
G
W
V
L
S
L
D
H
T
H
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122547
298
33975
T262
D
E
L
E
L
Y
E
T
D
Y
M
I
L
D
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181890
350
38433
E310
P
G
L
K
N
F
L
E
D
N
L
S
W
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.4
75
71.6
N.A.
89.3
81.3
N.A.
63.9
81.6
73.3
68.7
N.A.
N.A.
34.9
N.A.
35.2
Protein Similarity:
100
62.5
75.4
74.6
N.A.
94.6
86.1
N.A.
70.9
89.3
81.6
79.6
N.A.
N.A.
48.7
N.A.
51.2
P-Site Identity:
100
100
100
6.6
N.A.
73.3
73.3
N.A.
0
73.3
60
46.6
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
100
100
100
40
N.A.
86.6
80
N.A.
13.3
80
66.6
66.6
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
42
0
0
0
0
% C
% Asp:
17
0
0
0
0
0
0
0
17
9
0
0
0
9
9
% D
% Glu:
0
9
0
9
0
0
9
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
75
0
0
0
0
0
17
9
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
25
9
9
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
67
9
9
0
0
0
0
9
0
0
0
0
0
42
% K
% Leu:
0
9
84
0
9
17
75
0
9
9
9
0
17
17
9
% L
% Met:
0
0
0
0
0
0
0
0
59
0
9
0
0
0
0
% M
% Asn:
59
0
0
0
9
0
0
0
0
34
0
17
0
0
0
% N
% Pro:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
9
9
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
9
34
25
9
% R
% Ser:
9
0
0
0
9
0
9
59
9
25
17
50
0
25
9
% S
% Thr:
0
0
0
0
0
0
0
17
0
0
0
9
9
0
9
% T
% Val:
0
0
0
0
9
67
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
67
0
0
0
0
0
0
9
9
17
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
9
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _