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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO46
All Species:
0.61
Human Site:
S612
Identified Species:
1.67
UniProt:
Q6PJ61
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PJ61
NP_001073938
646
69031
S612
T
R
G
R
G
G
E
S
P
P
R
P
P
L
P
Chimpanzee
Pan troglodytes
XP_512757
555
59914
H533
P
G
C
R
L
G
L
H
D
N
N
W
V
L
P
Rhesus Macaque
Macaca mulatta
XP_001111140
603
64646
L580
T
P
G
C
R
L
G
L
H
D
N
N
W
V
L
Dog
Lupus familis
XP_855079
616
65616
G591
N
W
V
L
P
C
N
G
P
G
G
G
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG80
603
65275
L580
T
P
G
C
R
L
G
L
H
D
N
N
W
V
L
Rat
Rattus norvegicus
Q4KLY2
603
65220
L580
T
P
G
C
R
L
G
L
H
D
N
N
W
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026384
745
81040
N717
C
K
L
G
L
H
D
N
H
W
V
P
A
C
H
Frog
Xenopus laevis
NP_001092184
407
45544
D385
G
C
Q
L
G
L
H
D
N
N
W
V
L
P
G
Zebra Danio
Brachydanio rerio
NP_001076300
664
72937
T632
Y
W
M
C
C
R
R
T
D
K
D
T
P
G
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
92.2
90.4
N.A.
85.2
84.8
N.A.
N.A.
34.2
42.2
49.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
84.9
92.7
92.4
N.A.
88.2
87.9
N.A.
N.A.
43.7
49.3
60.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
13.3
6.6
N.A.
13.3
13.3
N.A.
N.A.
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
20
6.6
N.A.
20
20
N.A.
N.A.
26.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% A
% Cys:
12
12
12
45
12
12
0
0
0
0
0
0
0
12
12
% C
% Asp:
0
0
0
0
0
0
12
12
23
34
12
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
45
12
23
23
34
12
0
12
12
12
0
12
23
% G
% His:
0
0
0
0
0
12
12
12
45
0
0
0
0
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
0
% K
% Leu:
0
0
12
23
23
45
12
34
0
0
0
0
12
23
34
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
12
12
12
23
45
34
0
0
0
% N
% Pro:
12
34
0
0
12
0
0
0
23
12
0
23
23
12
23
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
0
23
34
12
12
0
0
0
12
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
12
0
0
0
0
12
12
0
% S
% Thr:
45
0
0
0
0
0
0
12
0
0
0
12
0
0
0
% T
% Val:
0
0
12
0
0
0
0
0
0
0
12
12
12
34
0
% V
% Trp:
0
23
0
0
0
0
0
0
0
12
12
12
34
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _