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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR59
All Species:
20
Human Site:
S636
Identified Species:
48.89
UniProt:
Q6PJI9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PJI9
NP_085058.3
974
109793
S636
S
K
R
E
G
S
D
S
G
N
R
Q
I
K
A
Chimpanzee
Pan troglodytes
XP_511107
975
109845
S637
S
K
R
E
G
S
D
S
G
N
R
Q
I
K
A
Rhesus Macaque
Macaca mulatta
XP_001109464
974
109687
S636
S
K
R
E
G
S
D
S
G
N
R
Q
I
K
A
Dog
Lupus familis
XP_536785
989
111509
A632
R
R
R
W
S
I
Q
A
I
N
D
F
P
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0M0
992
111708
S636
S
K
R
E
G
S
D
S
G
N
R
P
I
K
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512608
981
110580
S619
S
K
R
E
G
S
D
S
S
N
R
P
I
K
A
Chicken
Gallus gallus
Q5ZLG9
973
109864
A636
S
K
R
E
G
T
D
A
N
N
R
P
I
K
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKK2
989
110067
S654
A
Q
R
E
A
N
A
S
F
Y
L
Q
E
R
M
Honey Bee
Apis mellifera
XP_393825
1041
118507
Y649
Y
H
F
M
V
M
I
Y
D
A
S
S
L
F
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03897
1148
130928
D720
F
D
D
E
T
S
S
D
D
S
F
D
S
V
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.2
95.3
N.A.
94.5
N.A.
N.A.
91.9
88.9
N.A.
N.A.
N.A.
34.8
41.5
N.A.
N.A.
Protein Similarity:
100
99.5
99.6
96.8
N.A.
96
N.A.
N.A.
94.3
94.4
N.A.
N.A.
N.A.
52.5
58.8
N.A.
N.A.
P-Site Identity:
100
100
100
20
N.A.
93.3
N.A.
N.A.
86.6
73.3
N.A.
N.A.
N.A.
26.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
93.3
N.A.
N.A.
86.6
86.6
N.A.
N.A.
N.A.
53.3
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
10
20
0
10
0
0
0
0
70
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
60
10
20
0
10
10
0
0
0
% D
% Glu:
0
0
0
80
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
10
0
10
0
0
0
0
0
10
0
10
10
0
10
10
% F
% Gly:
0
0
0
0
60
0
0
0
40
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
10
0
10
0
0
0
60
0
0
% I
% Lys:
0
60
0
0
0
0
0
0
0
0
0
0
0
70
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% L
% Met:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
10
0
0
10
70
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
30
10
0
0
% P
% Gln:
0
10
0
0
0
0
10
0
0
0
0
40
0
0
0
% Q
% Arg:
10
10
80
0
0
0
0
0
0
0
60
0
0
10
0
% R
% Ser:
60
0
0
0
10
60
10
60
10
10
10
10
10
0
10
% S
% Thr:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _