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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR59 All Species: 26.36
Human Site: S795 Identified Species: 64.44
UniProt: Q6PJI9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PJI9 NP_085058.3 974 109793 S795 S G S C S S M S D P G L N T G
Chimpanzee Pan troglodytes XP_511107 975 109845 S796 S G S C S S M S D P G L N T G
Rhesus Macaque Macaca mulatta XP_001109464 974 109687 S795 S G S C S S M S D P G L S T G
Dog Lupus familis XP_536785 989 111509 S810 S G S C S S M S D P G L N A G
Cat Felis silvestris
Mouse Mus musculus Q8C0M0 992 111708 S813 S G S C S S M S D P G F N T G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512608 981 110580 S802 S G S C S S V S D P G L N T G
Chicken Gallus gallus Q5ZLG9 973 109864 S794 S G S C S S M S D P G L G T G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKK2 989 110067 Q804 K T V R L P P Q L N S Q I S P
Honey Bee Apis mellifera XP_393825 1041 118507 Q845 T E D K H L M Q K E I I D I I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03897 1148 130928 D948 G K N I H G G D N S S I R S D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 99.2 95.3 N.A. 94.5 N.A. N.A. 91.9 88.9 N.A. N.A. N.A. 34.8 41.5 N.A. N.A.
Protein Similarity: 100 99.5 99.6 96.8 N.A. 96 N.A. N.A. 94.3 94.4 N.A. N.A. N.A. 52.5 58.8 N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 N.A. N.A. 93.3 93.3 N.A. N.A. N.A. 0 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 N.A. N.A. 100 93.3 N.A. N.A. N.A. 6.6 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 70 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 10 70 0 0 0 10 0 10 % D
% Glu: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 10 70 0 0 0 10 10 0 0 0 70 0 10 0 70 % G
% His: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 10 20 10 10 10 % I
% Lys: 10 10 0 10 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 10 0 0 10 0 0 60 0 0 0 % L
% Met: 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 10 10 0 0 50 0 0 % N
% Pro: 0 0 0 0 0 10 10 0 0 70 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 20 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 70 0 70 0 70 70 0 70 0 10 20 0 10 20 0 % S
% Thr: 10 10 0 0 0 0 0 0 0 0 0 0 0 60 0 % T
% Val: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _