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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR59
All Species:
27.88
Human Site:
T558
Identified Species:
68.15
UniProt:
Q6PJI9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PJI9
NP_085058.3
974
109793
T558
V
Y
F
T
R
P
M
T
M
H
R
A
V
S
P
Chimpanzee
Pan troglodytes
XP_511107
975
109845
T559
V
Y
F
T
R
P
M
T
M
H
R
A
V
S
P
Rhesus Macaque
Macaca mulatta
XP_001109464
974
109687
T558
V
Y
F
T
R
P
M
T
M
H
R
A
V
S
P
Dog
Lupus familis
XP_536785
989
111509
T554
V
Y
F
T
R
P
M
T
M
H
R
A
V
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0M0
992
111708
T558
V
Y
F
T
R
P
M
T
M
H
R
A
V
S
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512608
981
110580
T541
V
Y
F
T
R
P
M
T
M
H
R
A
V
S
P
Chicken
Gallus gallus
Q5ZLG9
973
109864
T558
V
Y
F
T
R
P
M
T
M
H
R
A
V
S
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKK2
989
110067
R576
Q
L
L
L
Q
S
P
R
L
E
G
A
L
S
S
Honey Bee
Apis mellifera
XP_393825
1041
118507
S571
R
A
S
Y
T
R
R
S
S
M
K
P
E
C
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03897
1148
130928
K642
C
F
F
A
N
E
K
K
P
E
K
K
Q
N
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.2
95.3
N.A.
94.5
N.A.
N.A.
91.9
88.9
N.A.
N.A.
N.A.
34.8
41.5
N.A.
N.A.
Protein Similarity:
100
99.5
99.6
96.8
N.A.
96
N.A.
N.A.
94.3
94.4
N.A.
N.A.
N.A.
52.5
58.8
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
N.A.
N.A.
N.A.
13.3
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
N.A.
N.A.
N.A.
33.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
0
0
0
0
80
0
0
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
20
0
0
10
0
0
% E
% Phe:
0
10
80
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
70
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
10
0
0
20
10
0
0
0
% K
% Leu:
0
10
10
10
0
0
0
0
10
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
70
0
70
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
70
10
0
10
0
0
10
0
0
70
% P
% Gln:
10
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
10
0
0
0
70
10
10
10
0
0
70
0
0
0
0
% R
% Ser:
0
0
10
0
0
10
0
10
10
0
0
0
0
80
10
% S
% Thr:
0
0
0
70
10
0
0
70
0
0
0
0
0
0
10
% T
% Val:
70
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
70
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _