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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCLRE1A All Species: 13.03
Human Site: S194 Identified Species: 26.06
UniProt: Q6PJP8 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PJP8 NP_055696.3 1040 116422 S194 F S S P S P A S G G S F S E T
Chimpanzee Pan troglodytes XP_508045 1040 116405 S194 F S S P S P A S G G S F S E T
Rhesus Macaque Macaca mulatta XP_001090942 1039 116662 S194 F S S P S P A S G G S F S E T
Dog Lupus familis XP_535018 1074 119811 S220 V S S P A H P S G D C C H E T
Cat Felis silvestris
Mouse Mus musculus Q9JIC3 1026 113549 L193 L G S P S D A L A G L F A A A
Rat Rattus norvegicus NP_001099671 1026 112807 S185 L L A Q S R D S K E P L S P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513453 994 111830 F178 H Y K R Y S H F L L A Q R R A
Chicken Gallus gallus Q5QJC4 972 108310 K156 S T I P S H Y K R Y S H F L L
Frog Xenopus laevis NP_001093331 932 103215 P117 Y C P S C Q M P F S L L L V Q
Zebra Danio Brachydanio rerio XP_002664006 926 102909 Q111 S I L V V Q S Q Q W H V A E C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002321063 382 43088
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38961 484 55143
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 93.5 71.6 N.A. 62.8 61.8 N.A. 49.7 43.4 40.2 38.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 96 78.9 N.A. 72.5 72.5 N.A. 63.3 58.2 55.4 53.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 46.6 N.A. 40 20 N.A. 0 20 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 53.3 N.A. 46.6 33.3 N.A. 6.6 26.6 6.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 20.6 N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: 27.1 N.A. N.A. 34 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 0 N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 9 0 34 0 9 0 9 0 17 9 17 % A
% Cys: 0 9 0 0 9 0 0 0 0 0 9 9 0 0 9 % C
% Asp: 0 0 0 0 0 9 9 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 9 0 0 0 42 0 % E
% Phe: 25 0 0 0 0 0 0 9 9 0 0 34 9 0 0 % F
% Gly: 0 9 0 0 0 0 0 0 34 34 0 0 0 0 0 % G
% His: 9 0 0 0 0 17 9 0 0 0 9 9 9 0 0 % H
% Ile: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 9 0 0 0 0 9 9 0 0 0 0 0 0 % K
% Leu: 17 9 9 0 0 0 0 9 9 9 17 17 9 9 9 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 50 0 25 9 9 0 0 9 0 0 9 0 % P
% Gln: 0 0 0 9 0 17 0 9 9 0 0 9 0 0 9 % Q
% Arg: 0 0 0 9 0 9 0 0 9 0 0 0 9 9 0 % R
% Ser: 17 34 42 9 50 9 9 42 0 9 34 0 34 0 9 % S
% Thr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 34 % T
% Val: 9 0 0 9 9 0 0 0 0 0 0 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 9 9 0 0 9 0 9 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _