Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCLRE1A All Species: 9.09
Human Site: S245 Identified Species: 18.18
UniProt: Q6PJP8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PJP8 NP_055696.3 1040 116422 S245 S P S L T E A S E K I S T H I
Chimpanzee Pan troglodytes XP_508045 1040 116405 S245 S P S P T E A S E K I S T H I
Rhesus Macaque Macaca mulatta XP_001090942 1039 116662 S245 S P S P T K A S E K I S A N I
Dog Lupus familis XP_535018 1074 119811 T271 K F Q S P T E T N K K I S S S
Cat Felis silvestris
Mouse Mus musculus Q9JIC3 1026 113549 I244 T S Q P S A E I N R K N V S S
Rat Rattus norvegicus NP_001099671 1026 112807 L236 S L L M I Q C L K T S Q P P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513453 994 111830 L229 K V P N D P S L I T S G P R K
Chicken Gallus gallus Q5QJC4 972 108310 P207 E D S Q A E K P S K N L K N V
Frog Xenopus laevis NP_001093331 932 103215 Q168 Y S H F Q L A Q S R A V N D S
Zebra Danio Brachydanio rerio XP_002664006 926 102909 Q162 R A Q N D S V Q A I S D F S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002321063 382 43088
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38961 484 55143
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 93.5 71.6 N.A. 62.8 61.8 N.A. 49.7 43.4 40.2 38.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 96 78.9 N.A. 72.5 72.5 N.A. 63.3 58.2 55.4 53.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 73.3 6.6 N.A. 0 6.6 N.A. 0 20 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 86.6 20 N.A. 26.6 26.6 N.A. 6.6 33.3 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 20.6 N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: 27.1 N.A. N.A. 34 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 0 N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 9 34 0 9 0 9 0 9 0 9 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 17 0 0 0 0 0 0 9 0 9 0 % D
% Glu: 9 0 0 0 0 25 17 0 25 0 0 0 0 0 0 % E
% Phe: 0 9 0 9 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 17 0 % H
% Ile: 0 0 0 0 9 0 0 9 9 9 25 9 0 0 25 % I
% Lys: 17 0 0 0 0 9 9 0 9 42 17 0 9 0 9 % K
% Leu: 0 9 9 9 0 9 0 17 0 0 0 9 0 0 9 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 17 0 0 0 0 17 0 9 9 9 17 0 % N
% Pro: 0 25 9 25 9 9 0 9 0 0 0 0 17 9 0 % P
% Gln: 0 0 25 9 9 9 0 17 0 0 0 9 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 17 0 0 0 9 0 % R
% Ser: 34 17 34 9 9 9 9 25 17 0 25 25 9 25 25 % S
% Thr: 9 0 0 0 25 9 0 9 0 17 0 0 17 0 0 % T
% Val: 0 9 0 0 0 0 9 0 0 0 0 9 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _