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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCLRE1A All Species: 15.15
Human Site: S281 Identified Species: 30.3
UniProt: Q6PJP8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PJP8 NP_055696.3 1040 116422 S281 A L R L A N N S E H I N L P L
Chimpanzee Pan troglodytes XP_508045 1040 116405 S281 A L R L A H N S E H I N L P L
Rhesus Macaque Macaca mulatta XP_001090942 1039 116662 S281 A L R L E N N S E H I N L P L
Dog Lupus familis XP_535018 1074 119811 S316 E L G I L S N S E H I R S P L
Cat Felis silvestris
Mouse Mus musculus Q9JIC3 1026 113549 S276 D Q L V G G G S P L A E V A L
Rat Rattus norvegicus NP_001099671 1026 112807 L272 E F V K R D Q L V G S G S P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513453 994 111830 Q261 P A S Q K T L Q F P E P I G N
Chicken Gallus gallus Q5QJC4 972 108310 T239 L N I T S E S T S S F A D V Q
Frog Xenopus laevis NP_001093331 932 103215 I200 L N L S Q S P I S W V K I S E
Zebra Danio Brachydanio rerio XP_002664006 926 102909 S194 S A V N V S A S S S Q S S S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002321063 382 43088
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38961 484 55143
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 93.5 71.6 N.A. 62.8 61.8 N.A. 49.7 43.4 40.2 38.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 96 78.9 N.A. 72.5 72.5 N.A. 63.3 58.2 55.4 53.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 53.3 N.A. 13.3 13.3 N.A. 0 0 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 66.6 N.A. 26.6 20 N.A. 6.6 20 20 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 20.6 N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: 27.1 N.A. N.A. 34 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 0 N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 17 0 0 17 0 9 0 0 0 9 9 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 9 0 0 0 0 0 0 9 0 0 % D
% Glu: 17 0 0 0 9 9 0 0 34 0 9 9 0 0 9 % E
% Phe: 0 9 0 0 0 0 0 0 9 0 9 0 0 0 0 % F
% Gly: 0 0 9 0 9 9 9 0 0 9 0 9 0 9 0 % G
% His: 0 0 0 0 0 9 0 0 0 34 0 0 0 0 0 % H
% Ile: 0 0 9 9 0 0 0 9 0 0 34 0 17 0 0 % I
% Lys: 0 0 0 9 9 0 0 0 0 0 0 9 0 0 0 % K
% Leu: 17 34 17 25 9 0 9 9 0 9 0 0 25 0 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 17 0 9 0 17 34 0 0 0 0 25 0 0 9 % N
% Pro: 9 0 0 0 0 0 9 0 9 9 0 9 0 42 9 % P
% Gln: 0 9 0 9 9 0 9 9 0 0 9 0 0 0 9 % Q
% Arg: 0 0 25 0 9 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 9 0 9 9 9 25 9 50 25 17 9 9 25 17 0 % S
% Thr: 0 0 0 9 0 9 0 9 0 0 0 0 0 0 0 % T
% Val: 0 0 17 9 9 0 0 0 9 0 9 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _