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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCLRE1A All Species: 10.61
Human Site: S623 Identified Species: 21.21
UniProt: Q6PJP8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PJP8 NP_055696.3 1040 116422 S623 T L H E S Q L S V E L S S E R
Chimpanzee Pan troglodytes XP_508045 1040 116405 S623 T L H E S Q L S V E L S S E R
Rhesus Macaque Macaca mulatta XP_001090942 1039 116662 L622 S N L N E S Q L S V E L S S E
Dog Lupus familis XP_535018 1074 119811 P657 K N L N E S Q P S V E V S N E
Cat Felis silvestris
Mouse Mus musculus Q9JIC3 1026 113549 Q609 A K N L N E S Q H S V G L S G
Rat Rattus norvegicus NP_001099671 1026 112807 S609 N L N E S Q H S M E L S G E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513453 994 111830 S594 Q R K R L R E S D A L E E E V
Chicken Gallus gallus Q5QJC4 972 108310 R572 S V A P S G K R P R Q Q K R K
Frog Xenopus laevis NP_001093331 932 103215 E533 H D V A L P S E S K P G Q R K
Zebra Danio Brachydanio rerio XP_002664006 926 102909 S527 P S E G S G V S P A V E D S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002321063 382 43088
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38961 484 55143 L85 N L F Q I W G L Q E N S P D T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 93.5 71.6 N.A. 62.8 61.8 N.A. 49.7 43.4 40.2 38.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 96 78.9 N.A. 72.5 72.5 N.A. 63.3 58.2 55.4 53.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 6.6 N.A. 0 66.6 N.A. 20 6.6 0 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 6.6 N.A. 26.6 80 N.A. 26.6 26.6 13.3 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 20.6 N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: 27.1 N.A. N.A. 34 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 20 N.A. N.A.
P-Site Similarity: 0 N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 9 0 0 0 0 0 17 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 9 0 0 0 9 9 0 % D
% Glu: 0 0 9 25 17 9 9 9 0 34 17 17 9 34 17 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 17 9 0 0 0 0 17 9 0 9 % G
% His: 9 0 17 0 0 0 9 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 9 9 0 0 0 9 0 0 9 0 0 9 0 17 % K
% Leu: 0 34 17 9 17 0 17 17 0 0 34 9 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 17 17 17 17 9 0 0 0 0 0 9 0 0 9 0 % N
% Pro: 9 0 0 9 0 9 0 9 17 0 9 0 9 0 0 % P
% Gln: 9 0 0 9 0 25 17 9 9 0 9 9 9 0 0 % Q
% Arg: 0 9 0 9 0 9 0 9 0 9 0 0 0 17 25 % R
% Ser: 17 9 0 0 42 17 17 42 25 9 0 34 34 25 0 % S
% Thr: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % T
% Val: 0 9 9 0 0 0 9 0 17 17 17 9 0 0 17 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _