KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLRE1A
All Species:
16.06
Human Site:
S643
Identified Species:
32.12
UniProt:
Q6PJP8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PJP8
NP_055696.3
1040
116422
S643
K
R
C
R
K
S
N
S
L
Q
E
G
A
C
Q
Chimpanzee
Pan troglodytes
XP_508045
1040
116405
S643
K
R
C
R
K
S
N
S
L
Q
E
G
A
C
Q
Rhesus Macaque
Macaca mulatta
XP_001090942
1039
116662
S642
K
K
R
R
K
K
N
S
L
Q
E
G
V
Y
Q
Dog
Lupus familis
XP_535018
1074
119811
S677
K
R
L
K
K
S
D
S
L
E
E
G
T
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIC3
1026
113549
S629
R
R
K
R
H
K
T
S
N
S
P
R
E
G
P
Rat
Rattus norvegicus
NP_001099671
1026
112807
S629
K
R
H
K
K
S
N
S
P
Q
E
G
T
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513453
994
111830
K614
I
M
S
V
K
D
L
K
S
F
S
G
N
L
T
Chicken
Gallus gallus
Q5QJC4
972
108310
E592
E
D
L
E
A
V
E
E
S
S
N
K
D
G
G
Frog
Xenopus laevis
NP_001093331
932
103215
L553
S
L
G
D
K
D
P
L
A
D
H
T
N
T
E
Zebra Danio
Brachydanio rerio
XP_002664006
926
102909
R547
T
E
G
K
R
G
G
R
A
E
G
R
K
R
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321063
382
43088
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38961
484
55143
W105
Q
T
D
L
F
Q
S
W
G
L
Q
K
P
S
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
93.5
71.6
N.A.
62.8
61.8
N.A.
49.7
43.4
40.2
38.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
96
78.9
N.A.
72.5
72.5
N.A.
63.3
58.2
55.4
53.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
66.6
60
N.A.
20
66.6
N.A.
13.3
0
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
80
N.A.
26.6
73.3
N.A.
13.3
6.6
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.6
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
27.1
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
17
0
0
0
17
0
0
% A
% Cys:
0
0
17
0
0
0
0
0
0
0
0
0
0
17
0
% C
% Asp:
0
9
9
9
0
17
9
0
0
9
0
0
9
0
0
% D
% Glu:
9
9
0
9
0
0
9
9
0
17
42
0
9
0
9
% E
% Phe:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
17
0
0
9
9
0
9
0
9
50
0
17
9
% G
% His:
0
0
9
0
9
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
42
9
9
25
59
17
0
9
0
0
0
17
9
0
0
% K
% Leu:
0
9
17
9
0
0
9
9
34
9
0
0
0
9
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
34
0
9
0
9
0
17
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
9
0
9
0
9
9
17
% P
% Gln:
9
0
0
0
0
9
0
0
0
34
9
0
0
0
42
% Q
% Arg:
9
42
9
34
9
0
0
9
0
0
0
17
0
9
0
% R
% Ser:
9
0
9
0
0
34
9
50
17
17
9
0
0
9
0
% S
% Thr:
9
9
0
0
0
0
9
0
0
0
0
9
17
9
9
% T
% Val:
0
0
0
9
0
9
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _