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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNST All Species: 20.61
Human Site: Y586 Identified Species: 64.76
UniProt: Q6PJW8 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6PJW8 NP_001132931.1 725 79571 Y586 L S P E E A S Y S L Q E N L P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001100619 366 39646 S229 A L A D S H G S E N V L C G N
Dog Lupus familis XP_854662 713 78029 Y574 L S P E E A S Y S L Q E D L P
Cat Felis silvestris
Mouse Mus musculus Q8CBC4 711 76847 Y572 L S P E E A S Y S L Q E D L P
Rat Rattus norvegicus XP_001060344 823 88085 Y684 L S P E E A S Y S L Q E N L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513349 710 79080 Y573 L S P E E G S Y N L Q E T V S
Chicken Gallus gallus XP_419534 721 80108 Y582 I S P E R A S Y N S L E A L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697901 572 62623 N435 M E M E E N G N G L D F M N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 43.4 73.7 N.A. 68.1 54.4 N.A. 54.6 47.5 N.A. 29.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 46.4 81.2 N.A. 77.6 63.1 N.A. 67.1 61.6 N.A. 45.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 0 93.3 N.A. 93.3 100 N.A. 66.6 53.3 N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 6.6 100 N.A. 100 100 N.A. 80 66.6 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 13 0 0 63 0 0 0 0 0 0 13 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % C
% Asp: 0 0 0 13 0 0 0 0 0 0 13 0 25 0 0 % D
% Glu: 0 13 0 88 75 0 0 0 13 0 0 75 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % F
% Gly: 0 0 0 0 0 13 25 0 13 0 0 0 0 13 0 % G
% His: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % H
% Ile: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 63 13 0 0 0 0 0 0 0 75 13 13 0 63 0 % L
% Met: 13 0 13 0 0 0 0 0 0 0 0 0 13 0 0 % M
% Asn: 0 0 0 0 0 13 0 13 25 13 0 0 25 13 13 % N
% Pro: 0 0 75 0 0 0 0 0 0 0 0 0 0 0 50 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 63 0 0 0 0 % Q
% Arg: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 75 0 0 13 0 75 13 50 13 0 0 0 0 25 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 13 0 0 13 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _