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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS4L2
All Species:
8.79
Human Site:
T23
Identified Species:
24.17
UniProt:
Q6PKH6
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PKH6
NP_932349
230
24586
T23
R
L
A
S
S
R
M
T
R
R
D
P
L
T
N
Chimpanzee
Pan troglodytes
XP_001164583
263
28214
T25
R
M
A
S
S
G
M
T
R
R
D
P
L
A
N
Rhesus Macaque
Macaca mulatta
XP_001110187
278
29668
T25
R
M
A
S
S
G
M
T
R
R
D
P
L
A
N
Dog
Lupus familis
XP_547738
370
40035
D118
R
M
N
S
T
G
I
D
Q
K
G
V
L
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q99LB2
260
27736
A17
N
P
L
S
N
K
V
A
L
V
T
A
S
T
D
Rat
Rattus norvegicus
Q8VID1
260
27564
A17
N
P
L
A
N
K
V
A
L
V
T
A
S
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086342
261
27555
A18
K
K
L
Q
G
K
V
A
L
V
T
A
S
T
E
Zebra Danio
Brachydanio rerio
NP_956861
257
27155
T17
S
G
K
V
A
I
V
T
A
S
T
D
G
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LEU3
348
38131
K72
V
E
A
R
I
S
G
K
R
E
P
M
T
P
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.8
71.2
41.8
N.A.
63
62.3
N.A.
N.A.
N.A.
52.1
50.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
79
74
50
N.A.
69.2
69.2
N.A.
N.A.
N.A.
62.8
62.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
80
80
26.6
N.A.
13.3
6.6
N.A.
N.A.
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
86.6
60
N.A.
40
40
N.A.
N.A.
N.A.
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
45
12
12
0
0
34
12
0
0
34
0
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
34
12
0
0
23
% D
% Glu:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
12
34
12
0
0
0
12
0
12
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
12
12
0
0
0
0
0
0
12
0
% I
% Lys:
12
12
12
0
0
34
0
12
0
12
0
0
0
0
0
% K
% Leu:
0
12
34
0
0
0
0
0
34
0
0
0
45
0
0
% L
% Met:
0
34
0
0
0
0
34
0
0
0
0
12
0
0
0
% M
% Asn:
23
0
12
0
23
0
0
0
0
0
0
0
0
0
45
% N
% Pro:
0
23
0
0
0
0
0
0
0
0
12
34
0
12
12
% P
% Gln:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
45
0
0
12
0
12
0
0
45
34
0
0
0
0
0
% R
% Ser:
12
0
0
56
34
12
0
0
0
12
0
0
34
0
0
% S
% Thr:
0
0
0
0
12
0
0
45
0
0
45
0
12
45
0
% T
% Val:
12
0
0
12
0
0
45
0
0
34
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _