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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOK6
All Species:
13.64
Human Site:
S18
Identified Species:
37.5
UniProt:
Q6PKX4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PKX4
NP_689934.2
331
38318
S18
Q
G
Y
V
K
I
R
S
R
K
L
G
I
F
R
Chimpanzee
Pan troglodytes
XP_001169624
307
35639
R17
K
Q
G
Y
V
R
I
R
S
R
R
L
G
I
Y
Rhesus Macaque
Macaca mulatta
XP_001091477
306
35443
I16
V
K
Q
G
Y
V
R
I
R
S
R
R
L
G
I
Dog
Lupus familis
XP_533379
392
44570
L51
D
N
W
E
G
P
A
L
P
G
T
H
L
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q2MHE5
331
38268
S18
Q
G
Y
V
K
I
R
S
R
K
L
G
I
F
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509626
297
34314
Chicken
Gallus gallus
A3R064
426
47148
K19
V
Q
H
C
K
F
G
K
R
T
W
R
K
I
R
Frog
Xenopus laevis
NP_001080630
320
36761
S18
Q
G
Y
V
R
M
K
S
R
K
L
G
I
Y
R
Zebra Danio
Brachydanio rerio
NP_001082908
332
38492
S18
Q
G
Y
V
R
I
R
S
K
K
L
G
I
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.1
65.8
81.1
N.A.
99.6
N.A.
N.A.
62.5
20.8
52.8
81.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80
79.4
82.6
N.A.
99.6
N.A.
N.A.
75.2
35.2
70.3
90
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
13.3
0
N.A.
100
N.A.
N.A.
0
20
73.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
26.6
13.3
N.A.
100
N.A.
N.A.
0
26.6
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
0
0
0
34
0
% F
% Gly:
0
45
12
12
12
0
12
0
0
12
0
45
12
12
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
12
0
12
0
% H
% Ile:
0
0
0
0
0
34
12
12
0
0
0
0
45
23
12
% I
% Lys:
12
12
0
0
34
0
12
12
12
45
0
0
12
0
0
% K
% Leu:
0
0
0
0
0
0
0
12
0
0
45
12
23
0
0
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
12
% P
% Gln:
45
23
12
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
23
12
45
12
56
12
23
23
0
0
56
% R
% Ser:
0
0
0
0
0
0
0
45
12
12
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% T
% Val:
23
0
0
45
12
12
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% W
% Tyr:
0
0
45
12
12
0
0
0
0
0
0
0
0
12
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _