KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDMCP
All Species:
16.36
Human Site:
T127
Identified Species:
30
UniProt:
Q6Q0C1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6Q0C1
NP_997000.2
308
33435
T127
K
V
R
L
Q
T
Q
T
Q
A
Q
K
Q
Q
R
Chimpanzee
Pan troglodytes
XP_001159368
308
33445
T127
K
V
R
L
Q
T
Q
T
Q
A
Q
K
Q
Q
R
Rhesus Macaque
Macaca mulatta
XP_001113849
288
31847
L117
G
F
L
Q
A
Y
C
L
A
P
F
D
L
I
K
Dog
Lupus familis
XP_855336
388
41936
T199
K
V
R
L
Q
T
Q
T
Q
Q
R
R
P
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6IS41
310
33627
T127
K
V
R
L
Q
T
Q
T
Q
A
Q
T
Q
Q
R
Rat
Rattus norvegicus
Q6J329
310
33599
A127
K
V
R
L
Q
T
Q
A
Q
S
Q
T
Q
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512948
482
52245
K222
K
V
R
I
Q
T
E
K
K
Y
C
G
I
W
H
Chicken
Gallus gallus
XP_421367
330
35816
R162
K
V
R
M
Q
T
Q
R
N
P
H
P
S
V
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4QNX2
288
31518
T130
K
V
R
L
Q
C
Q
T
E
P
V
Q
H
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQG4
306
32934
I118
A
K
L
T
Y
P
Q
I
F
V
A
G
S
F
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27257
312
33116
T119
A
L
A
G
V
F
T
T
I
V
M
V
P
G
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93XM7
300
31004
L132
T
E
L
I
K
C
R
L
Q
A
Q
G
A
L
A
Baker's Yeast
Sacchar. cerevisiae
P32331
307
33357
S119
A
D
M
S
S
T
L
S
L
P
Q
Y
Y
A
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
43.1
68.5
N.A.
87.7
86.4
N.A.
37.7
54.8
N.A.
52.9
N.A.
20.4
N.A.
33.3
N.A.
Protein Similarity:
100
98.3
62
71.6
N.A.
91.2
90.6
N.A.
47.2
68.1
N.A.
66.2
N.A.
35.3
N.A.
48
N.A.
P-Site Identity:
100
100
0
60
N.A.
93.3
80
N.A.
33.3
40
N.A.
46.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
6.6
73.3
N.A.
93.3
86.6
N.A.
53.3
46.6
N.A.
60
N.A.
6.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.7
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
8
0
8
0
0
8
8
31
8
0
8
8
16
% A
% Cys:
0
0
0
0
0
16
8
0
0
0
8
0
0
0
8
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
8
0
0
0
0
8
0
8
0
0
0
0
0
8
% E
% Phe:
0
8
0
0
0
8
0
0
8
0
8
0
0
8
0
% F
% Gly:
8
0
0
8
0
0
0
0
0
0
0
24
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
8
% H
% Ile:
0
0
0
16
0
0
0
8
8
0
0
0
8
16
0
% I
% Lys:
62
8
0
0
8
0
0
8
8
0
0
16
0
0
8
% K
% Leu:
0
8
24
47
0
0
8
16
8
0
0
0
8
8
0
% L
% Met:
0
0
8
8
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
31
0
8
16
0
0
% P
% Gln:
0
0
0
8
62
0
62
0
47
8
47
8
31
31
0
% Q
% Arg:
0
0
62
0
0
0
8
8
0
0
8
8
0
0
31
% R
% Ser:
0
0
0
8
8
0
0
8
0
8
0
0
16
8
16
% S
% Thr:
8
0
0
8
0
62
8
47
0
0
0
16
0
0
8
% T
% Val:
0
62
0
0
8
0
0
0
0
16
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
8
8
0
0
0
8
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _