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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AQPEP
All Species:
14.85
Human Site:
S375
Identified Species:
29.7
UniProt:
Q6Q4G3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6Q4G3
NP_776161.3
990
113291
S375
T
D
I
I
A
L
P
S
F
D
N
H
A
M
E
Chimpanzee
Pan troglodytes
XP_001149318
990
113227
S375
T
D
I
I
A
L
P
S
F
D
N
H
A
M
E
Rhesus Macaque
Macaca mulatta
XP_001086413
990
113099
S375
A
D
I
I
A
L
P
S
F
D
N
H
A
M
E
Dog
Lupus familis
XP_538554
992
113412
T376
T
D
I
I
A
L
P
T
F
D
N
S
A
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Q2KHK3
559
63319
Rat
Rattus norvegicus
P15684
965
109430
A352
L
P
D
F
N
A
G
A
M
E
N
W
G
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
V253
T
A
L
S
N
M
P
V
K
S
T
T
Y
L
G
Chicken
Gallus gallus
XP_429201
929
106136
A343
K
V
S
D
R
K
T
A
I
A
L
I
V
S
H
Frog
Xenopus laevis
NP_001088591
963
109575
E359
W
G
L
V
T
Y
R
E
T
A
L
L
F
D
E
Zebra Danio
Brachydanio rerio
XP_682987
960
109411
T353
M
E
N
W
G
L
V
T
Y
R
E
T
A
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
E376
I
D
M
I
A
L
P
E
F
Q
A
G
A
M
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32454
935
105566
M349
I
Q
Y
P
L
P
K
M
D
N
V
A
V
H
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
94.2
80.4
N.A.
37.5
35.4
N.A.
33
50
34.2
35.3
N.A.
30.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
96.9
89.2
N.A.
45
53.3
N.A.
51.2
66.3
54.6
54.1
N.A.
50.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
0
6.6
N.A.
13.3
0
6.6
13.3
N.A.
60
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
0
26.6
N.A.
33.3
6.6
20
40
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
42
9
0
17
0
17
9
9
50
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
42
9
9
0
0
0
0
9
34
0
0
0
9
0
% D
% Glu:
0
9
0
0
0
0
0
17
0
9
9
0
0
0
59
% E
% Phe:
0
0
0
9
0
0
0
0
42
0
0
0
9
0
0
% F
% Gly:
0
9
0
0
9
0
9
0
0
0
0
9
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
25
0
9
9
% H
% Ile:
17
0
34
42
0
0
0
0
9
0
0
9
0
0
0
% I
% Lys:
9
0
0
0
0
9
9
0
9
0
0
0
0
0
0
% K
% Leu:
9
0
17
0
9
50
0
0
0
0
17
9
0
25
9
% L
% Met:
9
0
9
0
0
9
0
9
9
0
0
0
0
42
0
% M
% Asn:
0
0
9
0
17
0
0
0
0
9
42
0
0
0
0
% N
% Pro:
0
9
0
9
0
9
50
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
9
0
0
9
0
0
0
0
0
% R
% Ser:
0
0
9
9
0
0
0
25
0
9
0
9
0
9
0
% S
% Thr:
34
0
0
0
9
0
9
17
9
0
9
17
0
0
0
% T
% Val:
0
9
0
9
0
0
9
9
0
0
9
0
17
0
9
% V
% Trp:
9
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
9
0
0
9
0
0
9
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _