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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APOA5
All Species:
17.58
Human Site:
S278
Identified Species:
42.96
UniProt:
Q6Q788
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6Q788
NP_443200.2
366
41213
S278
G
P
D
P
Q
M
L
S
E
E
V
R
Q
R
L
Chimpanzee
Pan troglodytes
XP_522192
396
45424
G293
Q
K
S
L
A
E
L
G
G
H
L
D
Q
Q
V
Rhesus Macaque
Macaca mulatta
XP_001090079
366
41324
S278
G
P
D
P
Q
M
L
S
E
E
V
R
Q
R
L
Dog
Lupus familis
XP_546511
367
41348
S279
D
P
D
P
Q
M
L
S
Q
E
V
H
Q
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C7G5
368
41244
S275
S
L
D
P
Q
A
L
S
E
E
V
R
Q
R
L
Rat
Rattus norvegicus
Q9QUH3
367
41408
S275
S
L
D
P
Q
A
L
S
D
E
V
R
Q
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517346
266
30607
V179
R
D
R
L
R
G
H
V
E
E
L
R
Q
Q
L
Chicken
Gallus gallus
XP_417939
351
40333
G264
S
L
R
P
G
G
P
G
E
R
Y
A
E
E
M
Frog
Xenopus laevis
NP_001104214
343
40242
S248
E
L
K
Q
Q
L
V
S
Y
P
H
Q
I
K
Q
Zebra Danio
Brachydanio rerio
NP_001073330
255
29432
E168
E
E
L
R
G
N
L
E
Q
S
V
K
E
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.7
96.1
77.1
N.A.
72.5
71.3
N.A.
21
42.9
37.7
22.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
46.4
98
85
N.A.
79.6
79.8
N.A.
39.6
61.7
57.3
41.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
80
N.A.
80
73.3
N.A.
33.3
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
86.6
N.A.
80
80
N.A.
53.3
26.6
40
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
20
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
50
0
0
0
0
0
10
0
0
10
0
0
0
% D
% Glu:
20
10
0
0
0
10
0
10
50
60
0
0
20
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
0
0
0
20
20
0
20
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
10
10
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
10
10
0
0
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
0
40
10
20
0
10
70
0
0
0
20
0
0
10
60
% L
% Met:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
30
0
60
0
0
10
0
0
10
0
0
0
0
0
% P
% Gln:
10
0
0
10
60
0
0
0
20
0
0
10
70
20
20
% Q
% Arg:
10
0
20
10
10
0
0
0
0
10
0
50
0
50
0
% R
% Ser:
30
0
10
0
0
0
0
60
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
10
0
0
60
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _