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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBPL2
All Species:
12.42
Human Site:
S125
Identified Species:
17.08
UniProt:
Q6SJ96
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6SJ96
NP_950248.1
375
41524
S125
K
H
E
T
E
E
N
S
E
S
Q
S
P
Q
S
Chimpanzee
Pan troglodytes
A6H907
376
41488
S125
K
H
E
T
E
E
N
S
E
S
Q
S
P
Q
S
Rhesus Macaque
Macaca mulatta
XP_001088740
376
41563
S126
R
H
E
T
E
E
N
S
E
S
Q
S
P
Q
S
Dog
Lupus familis
XP_853710
344
38427
G113
L
P
R
E
Q
D
I
G
L
G
L
I
G
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6SJ95
350
38948
N119
D
E
H
G
S
E
L
N
L
N
S
N
S
S
P
Rat
Rattus norvegicus
A6H909
344
38336
L113
P
D
E
Q
G
S
G
L
N
L
N
S
N
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O13270
302
33116
Q71
A
A
Q
S
S
T
S
Q
Q
A
T
Q
G
T
S
Frog
Xenopus laevis
Q5UE94
320
35690
H89
T
P
S
Q
S
L
E
H
D
S
G
I
C
L
D
Zebra Danio
Brachydanio rerio
Q7SXL3
302
33001
G71
A
A
S
Q
Q
Q
G
G
M
V
G
G
S
G
Q
Tiger Blowfish
Takifugu rubipres
Q6SJ94
322
35702
V91
A
V
S
Q
D
S
A
V
C
L
D
Y
D
S
Q
Fruit Fly
Dros. melanogaster
P20227
353
38433
T122
Q
S
M
M
Q
P
Q
T
P
Q
S
M
M
A
H
Honey Bee
Apis mellifera
XP_623088
319
35720
T88
N
M
H
A
Y
A
T
T
P
T
F
A
T
P
Q
Nematode Worm
Caenorhab. elegans
P32085
340
36629
N109
P
G
S
V
M
H
H
N
L
D
I
N
P
P
S
Sea Urchin
Strong. purpuratus
P91809
265
29089
S33
S
H
Y
P
Q
I
S
S
Q
Q
S
Q
S
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P50159
200
22277
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28148
200
22378
Baker's Yeast
Sacchar. cerevisiae
P13393
240
26985
E9
A
D
E
E
R
L
K
E
F
K
E
A
N
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
95.4
78.6
N.A.
64.2
62.6
N.A.
N.A.
58.4
64.5
57.3
56.8
52.5
55.2
48
55.2
Protein Similarity:
100
98.6
96.8
82.1
N.A.
73.8
72.8
N.A.
N.A.
66.6
72.8
66.6
66.6
63.4
63.4
62.4
60.2
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
20
N.A.
N.A.
6.6
6.6
0
0
0
0
13.3
13.3
P-Site Similarity:
100
100
100
20
N.A.
26.6
20
N.A.
N.A.
40
13.3
13.3
6.6
20
20
33.3
33.3
Percent
Protein Identity:
N.A.
43.4
N.A.
42.6
45.6
N.A.
Protein Similarity:
N.A.
48.2
N.A.
47.7
54.9
N.A.
P-Site Identity:
N.A.
0
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
12
0
6
0
6
6
0
0
6
0
12
0
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
6
0
0
0
6
0
0
% C
% Asp:
6
12
0
0
6
6
0
0
6
6
6
0
6
0
6
% D
% Glu:
0
6
30
12
18
24
6
6
18
0
6
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
6
0
6
0
0
0
0
% F
% Gly:
0
6
0
6
6
0
12
12
0
6
12
6
12
6
0
% G
% His:
0
24
12
0
0
6
6
6
0
0
0
0
0
0
6
% H
% Ile:
0
0
0
0
0
6
6
0
0
0
6
12
0
0
6
% I
% Lys:
12
0
0
0
0
0
6
0
0
6
0
0
0
6
0
% K
% Leu:
6
0
0
0
0
12
6
6
18
12
6
0
0
6
6
% L
% Met:
0
6
6
6
6
0
0
0
6
0
0
6
6
0
0
% M
% Asn:
6
0
0
0
0
0
18
12
6
6
6
12
12
0
0
% N
% Pro:
12
12
0
6
0
6
0
0
12
0
0
0
24
12
6
% P
% Gln:
6
0
6
24
24
6
6
6
12
12
18
12
0
18
18
% Q
% Arg:
6
0
6
0
6
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
6
6
24
6
18
12
12
24
0
24
18
24
18
24
42
% S
% Thr:
6
0
0
18
0
6
6
12
0
6
6
0
6
6
0
% T
% Val:
0
6
0
6
0
0
0
6
0
6
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
0
6
0
0
0
0
0
0
6
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _