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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBPL2 All Species: 10
Human Site: S138 Identified Species: 13.75
UniProt: Q6SJ96 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6SJ96 NP_950248.1 375 41524 S138 Q S R L P S P S E Q D V G L G
Chimpanzee Pan troglodytes A6H907 376 41488 S138 Q S R L P S P S E Q D V G L G
Rhesus Macaque Macaca mulatta XP_001088740 376 41563 S139 Q S R L P S P S E Q D I G L G
Dog Lupus familis XP_853710 344 38427 H126 S S S L L N S H S H L Y P A D
Cat Felis silvestris
Mouse Mus musculus Q6SJ95 350 38948 L132 S P D P Q S C L C F D D A H S
Rat Rattus norvegicus A6H909 344 38336 C126 S S P D T Q S C L C S H D A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O13270 302 33116 L84 T S G Q T P Q L F H S Q T L T
Frog Xenopus laevis Q5UE94 320 35690 Q102 L D A S N L S Q P F T P S E C
Zebra Danio Brachydanio rerio Q7SXL3 302 33001 H84 G Q T P Q L Y H S T Q A V S T
Tiger Blowfish Takifugu rubipres Q6SJ94 322 35702 A104 S Q N S A T P A A T F D Q Q N
Fruit Fly Dros. melanogaster P20227 353 38433 E135 A H M M P M S E R S V G G S G
Honey Bee Apis mellifera XP_623088 319 35720 Q101 P Q S L M Q P Q T P Q N M M S
Nematode Worm Caenorhab. elegans P32085 340 36629 L122 P S V A Y Q N L T V P M T P L
Sea Urchin Strong. purpuratus P91809 265 29089 G46 Y L S V P S I G T P S F G S V
Poplar Tree Populus trichocarpa
Maize Zea mays P50159 200 22277
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P28148 200 22378
Baker's Yeast Sacchar. cerevisiae P13393 240 26985 T22 K I V F D P N T R Q V W E N Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 95.4 78.6 N.A. 64.2 62.6 N.A. N.A. 58.4 64.5 57.3 56.8 52.5 55.2 48 55.2
Protein Similarity: 100 98.6 96.8 82.1 N.A. 73.8 72.8 N.A. N.A. 66.6 72.8 66.6 66.6 63.4 63.4 62.4 60.2
P-Site Identity: 100 100 93.3 13.3 N.A. 13.3 6.6 N.A. N.A. 13.3 0 0 6.6 20 13.3 6.6 20
P-Site Similarity: 100 100 100 20 N.A. 13.3 6.6 N.A. N.A. 13.3 0 0 20 26.6 20 13.3 26.6
Percent
Protein Identity: N.A. 43.4 N.A. 42.6 45.6 N.A.
Protein Similarity: N.A. 48.2 N.A. 47.7 54.9 N.A.
P-Site Identity: N.A. 0 N.A. 0 6.6 N.A.
P-Site Similarity: N.A. 0 N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 6 6 6 0 0 6 6 0 0 6 6 12 0 % A
% Cys: 0 0 0 0 0 0 6 6 6 6 0 0 0 0 6 % C
% Asp: 0 6 6 6 6 0 0 0 0 0 24 12 6 0 12 % D
% Glu: 0 0 0 0 0 0 0 6 18 0 0 0 6 6 0 % E
% Phe: 0 0 0 6 0 0 0 0 6 12 6 6 0 0 0 % F
% Gly: 6 0 6 0 0 0 0 6 0 0 0 6 30 0 24 % G
% His: 0 6 0 0 0 0 0 12 0 12 0 6 0 6 0 % H
% Ile: 0 6 0 0 0 0 6 0 0 0 0 6 0 0 0 % I
% Lys: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 6 6 0 30 6 12 0 18 6 0 6 0 0 24 6 % L
% Met: 0 0 6 6 6 6 0 0 0 0 0 6 6 6 0 % M
% Asn: 0 0 6 0 6 6 12 0 0 0 0 6 0 6 6 % N
% Pro: 12 6 6 12 30 12 30 0 6 12 6 6 6 6 0 % P
% Gln: 18 18 0 6 12 18 6 12 0 24 12 6 6 6 6 % Q
% Arg: 0 0 18 0 0 0 0 0 12 0 0 0 0 0 0 % R
% Ser: 24 42 18 12 0 30 24 18 12 6 18 0 6 18 12 % S
% Thr: 6 0 6 0 12 6 0 6 18 12 6 0 12 0 12 % T
% Val: 0 0 12 6 0 0 0 0 0 6 12 12 6 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % W
% Tyr: 6 0 0 0 6 0 6 0 0 0 0 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _