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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBPL2
All Species:
11.21
Human Site:
S148
Identified Species:
15.42
UniProt:
Q6SJ96
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6SJ96
NP_950248.1
375
41524
S148
D
V
G
L
G
L
N
S
S
S
L
S
N
S
H
Chimpanzee
Pan troglodytes
A6H907
376
41488
S148
D
V
G
L
G
L
N
S
S
S
L
S
N
S
H
Rhesus Macaque
Macaca mulatta
XP_001088740
376
41563
S149
D
I
G
L
G
L
N
S
S
S
L
S
N
S
H
Dog
Lupus familis
XP_853710
344
38427
S136
L
Y
P
A
D
A
D
S
V
Q
P
S
L
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6SJ95
350
38948
P142
D
D
A
H
S
N
Q
P
S
P
E
T
P
N
S
Rat
Rattus norvegicus
A6H909
344
38336
Q136
S
H
D
A
D
S
N
Q
L
S
S
E
T
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O13270
302
33116
P94
S
Q
T
L
T
T
A
P
L
P
G
T
T
P
L
Frog
Xenopus laevis
Q5UE94
320
35690
A112
T
P
S
E
C
R
D
A
T
Q
D
S
S
N
L
Zebra Danio
Brachydanio rerio
Q7SXL3
302
33001
A94
Q
A
V
S
T
T
T
A
L
P
G
N
T
P
L
Tiger Blowfish
Takifugu rubipres
Q6SJ94
322
35702
L114
F
D
Q
Q
N
P
S
L
L
G
G
G
V
H
N
Fruit Fly
Dros. melanogaster
P20227
353
38433
G145
V
G
G
S
G
A
G
G
G
G
D
A
L
S
N
Honey Bee
Apis mellifera
XP_623088
319
35720
V111
Q
N
M
M
S
P
L
V
Q
N
T
N
H
I
A
Nematode Worm
Caenorhab. elegans
P32085
340
36629
S132
P
M
T
P
L
A
Y
S
V
Y
D
R
D
A
L
Sea Urchin
Strong. purpuratus
P91809
265
29089
V56
S
F
G
S
V
G
S
V
S
S
L
A
P
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P50159
200
22277
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28148
200
22378
Baker's Yeast
Sacchar. cerevisiae
P13393
240
26985
D32
V
W
E
N
Q
N
R
D
G
T
K
P
A
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
95.4
78.6
N.A.
64.2
62.6
N.A.
N.A.
58.4
64.5
57.3
56.8
52.5
55.2
48
55.2
Protein Similarity:
100
98.6
96.8
82.1
N.A.
73.8
72.8
N.A.
N.A.
66.6
72.8
66.6
66.6
63.4
63.4
62.4
60.2
P-Site Identity:
100
100
93.3
13.3
N.A.
13.3
13.3
N.A.
N.A.
6.6
6.6
0
0
20
0
6.6
26.6
P-Site Similarity:
100
100
100
20
N.A.
26.6
20
N.A.
N.A.
13.3
40
13.3
13.3
33.3
26.6
26.6
40
Percent
Protein Identity:
N.A.
43.4
N.A.
42.6
45.6
N.A.
Protein Similarity:
N.A.
48.2
N.A.
47.7
54.9
N.A.
P-Site Identity:
N.A.
0
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
12
0
18
6
12
0
0
0
12
6
6
6
% A
% Cys:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
12
6
0
12
0
12
6
0
0
18
0
6
0
0
% D
% Glu:
0
0
6
6
0
0
0
0
0
0
6
6
0
6
0
% E
% Phe:
6
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
6
30
0
24
6
6
6
12
12
18
6
0
6
0
% G
% His:
0
6
0
6
0
0
0
0
0
0
0
0
6
6
18
% H
% Ile:
0
6
0
0
0
0
0
0
0
0
0
0
0
6
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
6
% K
% Leu:
6
0
0
24
6
18
6
6
24
0
24
0
12
0
24
% L
% Met:
0
6
6
6
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
6
6
12
24
0
0
6
0
12
18
12
18
% N
% Pro:
6
6
6
6
0
12
0
12
0
18
6
6
12
18
0
% P
% Gln:
12
6
6
6
6
0
6
6
6
12
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
6
6
0
0
0
0
6
0
0
0
% R
% Ser:
18
0
6
18
12
6
12
30
30
30
6
30
6
24
12
% S
% Thr:
6
0
12
0
12
12
6
0
6
6
6
12
18
6
6
% T
% Val:
12
12
6
0
6
0
0
12
12
0
0
0
6
0
0
% V
% Trp:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
0
0
0
6
0
0
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _