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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBPL2
All Species:
14.85
Human Site:
S175
Identified Species:
20.42
UniProt:
Q6SJ96
Number Species:
16
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6SJ96
NP_950248.1
375
41524
S175
P
S
P
E
K
P
N
S
D
S
L
S
L
A
S
Chimpanzee
Pan troglodytes
A6H907
376
41488
S175
P
S
P
E
K
P
N
S
D
S
L
S
L
A
S
Rhesus Macaque
Macaca mulatta
XP_001088740
376
41563
S176
P
S
P
E
K
P
N
S
D
S
L
S
L
A
P
Dog
Lupus familis
XP_853710
344
38427
E163
T
P
M
T
P
V
S
E
C
S
G
I
V
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6SJ95
350
38948
F169
P
M
N
P
V
P
G
F
S
G
I
V
P
Q
L
Rat
Rattus norvegicus
A6H909
344
38336
E163
T
P
M
N
P
V
T
E
C
S
G
I
V
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O13270
302
33116
S121
P
A
T
P
A
S
E
S
S
G
I
V
P
Q
L
Frog
Xenopus laevis
Q5UE94
320
35690
S139
P
M
T
P
V
A
E
S
S
G
I
V
P
Q
L
Zebra Danio
Brachydanio rerio
Q7SXL3
302
33001
S121
P
A
T
P
A
S
E
S
S
G
I
V
P
Q
L
Tiger Blowfish
Takifugu rubipres
Q6SJ94
322
35702
E141
T
P
M
T
P
V
T
E
R
S
G
I
I
P
Q
Fruit Fly
Dros. melanogaster
P20227
353
38433
D172
P
A
T
P
G
S
A
D
P
G
I
V
P
Q
L
Honey Bee
Apis mellifera
XP_623088
319
35720
A138
T
P
M
T
P
A
S
A
D
P
G
I
L
P
Q
Nematode Worm
Caenorhab. elegans
P32085
340
36629
S159
M
V
P
A
T
P
A
S
Q
L
D
I
P
M
P
Sea Urchin
Strong. purpuratus
P91809
265
29089
E83
P
A
T
P
A
S
S
E
S
S
G
I
V
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P50159
200
22277
S19
V
D
L
S
K
H
P
S
G
I
V
P
T
L
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28148
200
22378
S19
V
D
L
T
K
H
P
S
G
I
V
P
T
L
Q
Baker's Yeast
Sacchar. cerevisiae
P13393
240
26985
A59
E
S
E
K
D
T
S
A
T
S
G
I
V
P
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
95.4
78.6
N.A.
64.2
62.6
N.A.
N.A.
58.4
64.5
57.3
56.8
52.5
55.2
48
55.2
Protein Similarity:
100
98.6
96.8
82.1
N.A.
73.8
72.8
N.A.
N.A.
66.6
72.8
66.6
66.6
63.4
63.4
62.4
60.2
P-Site Identity:
100
100
93.3
6.6
N.A.
13.3
6.6
N.A.
N.A.
13.3
13.3
13.3
6.6
6.6
13.3
20
13.3
P-Site Similarity:
100
100
93.3
20
N.A.
20
13.3
N.A.
N.A.
26.6
20
26.6
13.3
20
26.6
20
33.3
Percent
Protein Identity:
N.A.
43.4
N.A.
42.6
45.6
N.A.
Protein Similarity:
N.A.
48.2
N.A.
47.7
54.9
N.A.
P-Site Identity:
N.A.
13.3
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
20
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
0
6
18
12
12
12
0
0
0
0
0
18
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
6
0
0
6
24
0
6
0
0
0
0
% D
% Glu:
6
0
6
18
0
0
18
24
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
6
0
6
0
12
30
36
0
0
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
30
42
6
0
0
% I
% Lys:
0
0
0
6
30
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
12
0
0
0
0
0
0
6
18
0
24
12
30
% L
% Met:
6
12
24
0
0
0
0
0
0
0
0
0
0
6
0
% M
% Asn:
0
0
6
6
0
0
18
0
0
0
0
0
0
0
0
% N
% Pro:
53
24
24
36
24
30
12
0
6
6
0
12
36
36
12
% P
% Gln:
0
0
0
0
0
0
0
0
6
0
0
0
0
30
42
% Q
% Arg:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% R
% Ser:
0
24
0
6
0
24
24
53
30
48
0
18
0
0
12
% S
% Thr:
24
0
30
24
6
6
12
0
6
0
0
0
12
0
6
% T
% Val:
12
6
0
0
12
18
0
0
0
0
12
30
24
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _