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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBPL2
All Species:
9.09
Human Site:
T259
Identified Species:
12.5
UniProt:
Q6SJ96
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6SJ96
NP_950248.1
375
41524
T259
S
S
G
K
M
V
C
T
G
A
K
S
E
E
Q
Chimpanzee
Pan troglodytes
A6H907
376
41488
T259
S
S
G
K
M
V
C
T
G
A
K
S
E
E
Q
Rhesus Macaque
Macaca mulatta
XP_001088740
376
41563
T260
S
S
G
K
M
V
C
T
G
A
K
S
E
E
Q
Dog
Lupus familis
XP_853710
344
38427
A239
S
E
E
Q
S
R
L
A
A
R
K
Y
A
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6SJ95
350
38948
A245
E
E
E
S
R
L
A
A
R
K
Y
A
R
V
V
Rat
Rattus norvegicus
A6H909
344
38336
A239
S
E
D
E
S
R
L
A
A
R
K
Y
A
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O13270
302
33116
A197
E
E
Q
S
R
L
A
A
R
K
Y
A
R
V
V
Frog
Xenopus laevis
Q5UE94
320
35690
A215
E
E
Q
S
R
L
A
A
R
K
Y
A
R
V
V
Zebra Danio
Brachydanio rerio
Q7SXL3
302
33001
A197
E
E
Q
S
R
L
A
A
R
K
Y
A
R
V
V
Tiger Blowfish
Takifugu rubipres
Q6SJ94
322
35702
A217
S
E
E
Q
S
R
L
A
A
R
K
Y
A
R
V
Fruit Fly
Dros. melanogaster
P20227
353
38433
A248
E
D
D
S
R
L
A
A
R
K
Y
A
R
I
I
Honey Bee
Apis mellifera
XP_623088
319
35720
A214
S
E
E
D
S
R
L
A
A
R
K
Y
A
R
I
Nematode Worm
Caenorhab. elegans
P32085
340
36629
L235
K
S
E
E
A
S
R
L
A
A
R
K
Y
A
R
Sea Urchin
Strong. purpuratus
P91809
265
29089
A160
E
D
N
S
R
L
A
A
R
K
Y
A
R
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P50159
200
22277
R95
Q
Q
S
K
L
A
A
R
K
Y
A
R
I
I
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28148
200
22378
R95
H
L
S
K
L
A
A
R
K
Y
A
R
I
V
Q
Baker's Yeast
Sacchar. cerevisiae
P13393
240
26985
A135
S
E
D
D
S
K
L
A
S
R
K
Y
A
R
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
95.4
78.6
N.A.
64.2
62.6
N.A.
N.A.
58.4
64.5
57.3
56.8
52.5
55.2
48
55.2
Protein Similarity:
100
98.6
96.8
82.1
N.A.
73.8
72.8
N.A.
N.A.
66.6
72.8
66.6
66.6
63.4
63.4
62.4
60.2
P-Site Identity:
100
100
100
13.3
N.A.
0
13.3
N.A.
N.A.
0
0
0
13.3
0
13.3
13.3
0
P-Site Similarity:
100
100
100
20
N.A.
13.3
20
N.A.
N.A.
13.3
13.3
13.3
20
13.3
13.3
33.3
13.3
Percent
Protein Identity:
N.A.
43.4
N.A.
42.6
45.6
N.A.
Protein Similarity:
N.A.
48.2
N.A.
47.7
54.9
N.A.
P-Site Identity:
N.A.
13.3
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
6
12
48
65
30
24
12
36
30
6
0
% A
% Cys:
0
0
0
0
0
0
18
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
18
12
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
36
53
30
12
0
0
0
0
0
0
0
0
18
18
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
18
0
0
0
0
0
18
0
0
0
0
0
0
% G
% His:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
18
% I
% Lys:
6
0
0
30
0
6
0
0
12
36
48
6
0
0
0
% K
% Leu:
0
6
0
0
12
36
30
6
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
18
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
6
6
18
12
0
0
0
0
0
0
0
0
0
0
30
% Q
% Arg:
0
0
0
0
36
24
6
12
36
30
6
12
36
30
6
% R
% Ser:
48
24
12
36
30
6
0
0
6
0
0
18
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
18
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
18
0
0
0
0
0
0
0
36
48
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
36
30
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _