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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A25
All Species:
18.18
Human Site:
T316
Identified Species:
44.44
UniProt:
Q6T423
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6T423
NP_955384.3
547
61008
T316
K
N
A
E
D
I
L
T
M
E
V
L
K
S
T
Chimpanzee
Pan troglodytes
XP_522041
533
59566
R300
E
E
G
L
K
E
L
R
K
A
A
H
R
N
G
Rhesus Macaque
Macaca mulatta
XP_001084980
550
60036
T312
H
K
E
A
K
N
L
T
I
E
V
L
M
S
S
Dog
Lupus familis
XP_533255
552
61678
T316
K
N
A
G
E
A
L
T
M
E
V
L
R
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFZ5
553
60176
T316
K
A
E
G
D
T
L
T
M
E
V
L
R
S
A
Rat
Rattus norvegicus
Q3ZAV1
553
60226
T316
K
A
E
A
D
T
L
T
V
E
V
L
R
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507099
556
61556
T316
A
V
A
K
G
C
L
T
I
E
M
L
R
S
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66J54
558
62434
T310
E
E
E
G
E
K
I
T
L
E
S
M
R
S
D
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
D313
S
A
E
G
D
K
I
D
L
E
M
L
Q
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCA2
548
60985
V304
N
E
I
Y
E
Q
L
V
D
E
V
A
E
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
44.5
65.4
N.A.
44.2
45.9
N.A.
44.4
N.A.
38.3
34.8
N.A.
27.7
N.A.
N.A.
N.A.
Protein Similarity:
100
95.4
61.8
76.9
N.A.
59.8
62.2
N.A.
60.9
N.A.
59.8
56
N.A.
50.5
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
40
73.3
N.A.
60
53.3
N.A.
40
N.A.
20
20
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
53.3
86.6
N.A.
66.6
66.6
N.A.
66.6
N.A.
60
53.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
30
30
20
0
10
0
0
0
10
10
10
0
0
20
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
40
0
0
10
10
0
0
0
0
0
10
% D
% Glu:
20
30
50
10
30
10
0
0
0
90
0
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
40
10
0
0
0
0
0
0
0
0
0
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
10
0
0
10
20
0
20
0
0
0
0
0
0
% I
% Lys:
40
10
0
10
20
20
0
0
10
0
0
0
10
10
10
% K
% Leu:
0
0
0
10
0
0
80
0
20
0
0
70
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
30
0
20
10
10
0
0
% M
% Asn:
10
20
0
0
0
10
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
60
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
0
10
0
0
70
20
% S
% Thr:
0
0
0
0
0
20
0
70
0
0
0
0
0
0
20
% T
% Val:
0
10
0
0
0
0
0
10
10
0
60
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _