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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHL17 All Species: 16.06
Human Site: S299 Identified Species: 32.12
UniProt: Q6TDP4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6TDP4 NP_938073.1 642 69874 S299 L G H V D A E S L V R H H P D
Chimpanzee Pan troglodytes XP_520840 626 68231 S299 L G H V D A E S L V R H H P D
Rhesus Macaque Macaca mulatta XP_001087862 580 62778 Y257 V P S E E E V Y R A V L S W V
Dog Lupus familis XP_546727 669 72767 S326 L G H V D A E S L V R H H P D
Cat Felis silvestris
Mouse Mus musculus Q8VCK5 604 67393 P270 V G T V G S D P L I K S D E E
Rat Rattus norvegicus Q8K430 640 69714 S297 L G H V D A E S L V R H H P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515196 722 79884 P388 V G T V G S D P L I K S D E E
Chicken Gallus gallus XP_417591 590 65056 E261 E C K D L L I E A L K Y H L M
Frog Xenopus laevis Q6NRH0 564 63190 S241 A E P L I R C S L Q C R D L V
Zebra Danio Brachydanio rerio Q5U374 564 62914 S241 A E P L I R C S L P C R D L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 L279 V G T V G S D L L V R S D E A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794711 642 69880 P302 V T Q V E A H P I V Q Q C N G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94 88.6 94.1 N.A. 45.4 97.8 N.A. 42.2 84.2 37.2 36.9 N.A. 44.5 N.A. N.A. 52.3
Protein Similarity: 100 95 88.9 95.2 N.A. 61 98.5 N.A. 57.3 89.2 53.8 53.2 N.A. 59.3 N.A. N.A. 70.8
P-Site Identity: 100 100 0 100 N.A. 20 100 N.A. 20 6.6 13.3 13.3 N.A. 33.3 N.A. N.A. 20
P-Site Similarity: 100 100 13.3 100 N.A. 60 100 N.A. 60 26.6 20 20 N.A. 53.3 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 0 42 0 0 9 9 0 0 0 0 9 % A
% Cys: 0 9 0 0 0 0 17 0 0 0 17 0 9 0 0 % C
% Asp: 0 0 0 9 34 0 25 0 0 0 0 0 42 0 34 % D
% Glu: 9 17 0 9 17 9 34 9 0 0 0 0 0 25 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 59 0 0 25 0 0 0 0 0 0 0 0 0 9 % G
% His: 0 0 34 0 0 0 9 0 0 0 0 34 42 0 0 % H
% Ile: 0 0 0 0 17 0 9 0 9 17 0 0 0 0 0 % I
% Lys: 0 0 9 0 0 0 0 0 0 0 25 0 0 0 0 % K
% Leu: 34 0 0 17 9 9 0 9 75 9 0 9 0 25 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 9 17 0 0 0 0 25 0 9 0 0 0 34 0 % P
% Gln: 0 0 9 0 0 0 0 0 0 9 9 9 0 0 0 % Q
% Arg: 0 0 0 0 0 17 0 0 9 0 42 17 0 0 0 % R
% Ser: 0 0 9 0 0 25 0 50 0 0 0 25 9 0 0 % S
% Thr: 0 9 25 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 42 0 0 67 0 0 9 0 0 50 9 0 0 0 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _