KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASC1
All Species:
10.91
Human Site:
S227
Identified Species:
34.29
UniProt:
Q6TDU7
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6TDU7
NP_001076441.1
716
83218
S227
K
K
N
P
R
H
R
S
V
R
F
S
E
T
Q
Chimpanzee
Pan troglodytes
XP_520802
883
101408
S394
K
K
N
P
R
H
R
S
V
R
F
S
E
T
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543757
718
82671
Q228
P
E
A
E
K
L
K
Q
D
T
R
L
L
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6TDU8
730
84948
S232
K
K
N
P
R
H
R
S
V
R
F
S
E
T
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514489
364
41646
Chicken
Gallus gallus
XP_416435
660
76295
R198
A
V
S
S
I
A
V
R
I
L
H
T
H
Y
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A6H8T2
731
84203
G230
N
K
N
P
R
F
K
G
Y
K
F
E
E
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176259
678
77267
T204
H
F
S
H
R
C
R
T
F
K
L
K
R
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.1
N.A.
51.6
N.A.
67.1
N.A.
N.A.
26.8
44.4
N.A.
39.9
N.A.
N.A.
N.A.
N.A.
32.4
Protein Similarity:
100
80.9
N.A.
64.9
N.A.
81.9
N.A.
N.A.
37.2
64.2
N.A.
60
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
N.A.
N.A.
0
0
N.A.
40
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
33.3
N.A.
100
N.A.
N.A.
0
20
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
13
0
0
13
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
13
% D
% Glu:
0
13
0
13
0
0
0
0
0
0
0
13
50
0
0
% E
% Phe:
0
13
0
0
0
13
0
0
13
0
50
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
13
% G
% His:
13
0
0
13
0
38
0
0
0
0
13
0
13
0
0
% H
% Ile:
0
0
0
0
13
0
0
0
13
0
0
0
0
0
0
% I
% Lys:
38
50
0
0
13
0
25
0
0
25
0
13
0
0
0
% K
% Leu:
0
0
0
0
0
13
0
0
0
13
13
13
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
13
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
50
% Q
% Arg:
0
0
0
0
63
0
50
13
0
38
13
0
13
0
13
% R
% Ser:
0
0
25
13
0
0
0
38
0
0
0
38
0
13
0
% S
% Thr:
0
0
0
0
0
0
0
13
0
13
0
13
0
38
0
% T
% Val:
0
13
0
0
0
0
13
0
38
0
0
0
0
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
13
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _